Nanodisc Human PTGDR2-Strep Protein (HDFP861)
- SKU:
- HDFP861
- Size:
- 10μg
- Target:
- PTGDR2
- Tag:
- C-Flag&Strep Tag
- Expression Host:
- HEK293
- Conjugate:
- Unconjugated
Frequently bought together:
Description
| Product Name: | Nanodisc Human PTGDR2-Strep Protein |
| SKU: | HDFP861 |
| Size: | 10μg |
| Target: | PTGDR2 |
| Tag: | C-Flag&Strep Tag |
| Expression Host: | HEK293 |
| Conjugate: | Unconjugated |
| Synonyms: | CD294; CRTH2; DL1R; DP2; GPR44 |
| Protein Families: | Druggable Genome, GPCR, Transmembrane. |
| Protein Description: | Human PTGDR2-Strep full length protein-synthetic nanodisc |
| Molecular Weight: | The human full length PTGDR2-Strep protein has a MW of 43.3 kDa |
The protein is a G-protein-coupled receptor that is preferentially expressed in CD4 effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.
| Uniprot ID: | Q9Y5Y4 |
| Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Usage: | Research use only |
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