Human Prolactin Recombinant Protein (RPPB0870)
- SKU:
- RPPB0870
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- P01236
- Research Area:
- Growth Factors & Cytokines
Description
| Product Name: | Human Prolactin Recombinant Protein |
| Product Code: | RPPB0870 |
| Size: | 20µg |
| Species: | Human |
| Target: | Prolactin |
| Synonyms: | Mammotropin, Luteotropic hormone, Luteotropin, PRL. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | Prolactin His is supplied in 1x PBS and 50% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles. |
| Purity: | Greater than 95.0% as determined by(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE. |
Prolactin is a neuroendocrine hormone synthesized primarily by the pituitary gland but also a variety of other cell types including the placenta, brain and uterus. Its primary function is to promote and maintain lactation but has also been shown to have a role in breast cancer development, regulation of reproductive function and immunoregulation.
Prolactin-His Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 199 amino acids fragment (29-227) and having a molecular mass of 23 kDa with an amino-terminal hexahistidine tag. The Prolactin is purified by proprietary chromatographic techniques.
| UniProt Protein Function: | prolactin: Prolactin acts primarily on the mammary gland by promoting lactation. Belongs to the somatotropin/prolactin family. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted; Cytokine; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 6p22.3 Cellular Component: extracellular region Molecular Function:protein binding; prolactin receptor binding; hormone activity Biological Process: lactation; cell proliferation; cell surface receptor linked signal transduction; regulation of multicellular organism growth; positive regulation of JAK-STAT cascade; female pregnancy |
| NCBI Summary: | This gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011] |
| UniProt Code: | P01236 |
| NCBI GenInfo Identifier: | 130930 |
| NCBI Gene ID: | 5617 |
| NCBI Accession: | P01236.1 |
| UniProt Secondary Accession: | P01236,Q15199, Q92996, |
| UniProt Related Accession: | P01236 |
| Molecular Weight: | 25,876 Da |
| NCBI Full Name: | Prolactin |
| NCBI Synonym Full Names: | prolactin |
| NCBI Official Symbol: | PRL�� |
| NCBI Protein Information: | prolactin; decidual prolactin |
| UniProt Protein Name: | Prolactin |
| UniProt Gene Name: | PRL�� |
| UniProt Entry Name: | PRL_HUMAN |
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