Nanodisc Human PLA2R1 Protein (HDFP127)
- SKU:
- HDFP127
- Product Type:
- Recombinant Protein
- Protein Type:
- Full-Length Bioactive Membrane Protein
- Species:
- Human
- Uniprot:
- Q13018
Frequently bought together:
Description
system_update_altDatasheet
Product name | Human PLA2R1 full length protein-synthetic nanodisc |
Size: | 10ug |
Product SKU: | HDFP127 |
Product Category | Full Length Transmembrane Proteins |
Target: | PLA2R1 |
Uniprot: | Q13018 |
Description: | Human PLA2R1 full length protein-synthetic nanodisc |
Molecular Weight: | The human full length PLA2R1 protein has a MW of 168.6 kDa |
Protein Family: | Druggable Genome, Transmembrane |
Protein Pathways: | |
Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Synonyms: | CLEC13C; PLA2-R; PLA2G1R; PLA2IR; PLA2R |
Expression System: | HEK293 |
Formulation: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
Background: | This protein is a phospholipase A2 receptor. The protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. Polymorphisms at this locus have been associated with susceptibility to idiopathic membranous nephropathy. Alternatively spliced transcript variants encoding different isoforms have been identified. |
Delivery: | In Stock |
Usage | Research use only |