Human PLA2G7/PAF-AH/Lp-PLA2 Polyclonal Antibody (CAB24499)
The PLA2G7 Polyclonal Antibody is a valuable tool for researchers studying the PLA2G7 enzyme, also known as platelet-activating factor acetylhydrolase. This enzyme plays a crucial role in lipid metabolism and inflammation regulation. The antibody, derived from rabbit sources, exhibits high specificity and sensitivity for human samples, making it an ideal choice for Western blot applications.By targeting the PLA2G7 protein, this antibody enables precise detection and analysis in various cell types, providing valuable insights into lipid signaling pathways and inflammatory processes.
Understanding the function of PLA2G7 is essential for investigating its potential role in conditions such as cardiovascular disease, inflammation, and metabolic disorders.Researchers interested in lipid biology, inflammation, and metabolic regulation will find the PLA2G7 Polyclonal Antibody to be a reliable tool for their studies. Its versatility and specificity make it a valuable asset for exploring the intricate mechanisms governed by the PLA2G7 enzyme.
Product Name:
Human PLA2G7/PAF-AH/Lp-PLA2 Polyclonal Antibody
SKU:
CAB24499
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 22-441 of human PLA2G7/PAF-AH/Lp-PLA2 (NP_005075.3).
PLA2G7; LDL-PLA2; LP-PLA2; PAFAD; PAFAH; phospholipase A2 group VII; Human PLA2G7/PAF-AH/Lp-PLA2
Positive Sample:
Human plasma
Conjugate:
Unconjugated
Cellular Localization:
Secreted, extracellular space
Calculated MW:
50kDa
Observed MW:
60kDa
The protein encoded by this gene is a secreted enzyme that catalyzes the degradation of platelet-activating factor to biologically inactive products. Defects in this gene are a cause of platelet-activating factor acetylhydrolase deficiency. Two transcript variants encoding the same protein have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
7941
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of Human plasma, using Human PLA2G7/PAF-AH/Lp-PLA2 Rabbit pAb (CAB24499) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
