Description
Product Name: | Nanodisc Human PI2R Protein |
SKU: | HDFP437 |
Size: | 10μg |
Target: | PI2R |
Tag: | C-Flag Tag |
Expression Host: | HEK293 |
Conjugate: | Unconjugated |
Synonyms: | IP, PRIPR |
Protein Families: | GPCR, Transmembrane, Druggable Genome. |
Protein Description: | Human PI2R full length protein-synthetic nanodisc |
Protein Pathways: | GPCRDB Class A Rhodopsin-like, Prostaglandin synthesis regulation, Small ligand GPCRs, Metabolic and Obesity. |
Molecular Weight: | The human full length PI2R protein has a MW of 41kDa |
The protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor. [provided by RefSeq, Jul 2008]
Uniprot ID: | P43119 |
Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Usage: | Research use only |