Human PDZD11 Recombinant Protein (RPPB4218)
- SKU:
- RPPB4218
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q5EBL8
Description
| Product Name: | Human PDZD11 Recombinant Protein |
| Product Code: | RPPB4218 |
| Size: | 10µg |
| Species: | Human |
| Target: | PDZD11 |
| Synonyms: | PDZ domain-containing protein 11, ATPase-interacting PDZ protein, Plasma membrane calcium ATPase-interacting single-PDZ protein, PMCA-interacting single-PDZ protein, PDZD11, AIPP1, PDZK11, PISP. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | PDZD11 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 20% glycerol and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMDSRIPY DDYPVVFLPA YENPPAWIPP HERVHHPDYN NELTQFLPRT ITLKKPPGAQ LGFNIRGGKA SQLGIFISKV IPDSDAHRAG LQEGDQVLAV NDVDFQDIEH SKAVEILKTA REISMRVRFF PYNYHRQKER TVH |
PDZ Domain Containing 11 (PDZD11) is a cytosolic protein which contains one PDZ (DHR) domain. PDZD11 displays a resemblance to members of the MALS / VELIS family of proteins. PDZD11 contains but one PDZ domain which seemingly interacts with the C-terminus of partner proteins. PDZD11 is ubiquitously expressed and targets calcium and copper ATPases to basolateral cell membranes. PDZD11 is a briefly interacting partner of the PMCA b-splice forms which have a role in their sorting to or from the plasma membrane.
PDZD11 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 163 amino acids (1-140 a.a) and having a molecular mass of 18.5kDa.PDZD11 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | PDZD11: 2 isoforms of the human protein are produced by alternative splicing.Protein type: Adaptor/scaffoldChromosomal Location of Human Ortholog: Xq13.1Cellular Component: basolateral plasma membrane; cytosol; intercellular junction; synapseMolecular Function: protein bindingBiological Process: antimicrobial humoral response; biotin metabolic process; maintenance of epithelial cell polarity; neurotransmitter secretion; pantothenate metabolic process; transmembrane transport |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q5EBL8 |
| NCBI GenInfo Identifier: | 7706025 |
| NCBI Gene ID: | 51248 |
| NCBI Accession: | NP_057568.1 |
| UniProt Secondary Accession: | Q5EBL8,Q6UWE1, Q9P0Q1, D3DVU3 |
| UniProt Related Accession: | Q5EBL8 |
| Molecular Weight: | 32.1kD |
| NCBI Full Name: | PDZ domain-containing protein 11 |
| NCBI Synonym Full Names: | PDZ domain containing 11 |
| NCBI Official Symbol: | PDZD11�� |
| NCBI Official Synonym Symbols: | PISP; AIPP1; PDZK11�� |
| NCBI Protein Information: | PDZ domain-containing protein 11 |
| UniProt Protein Name: | PDZ domain-containing protein 11 |
| UniProt Synonym Protein Names: | ATPase-interacting PDZ protein; Plasma membrane calcium ATPase-interacting single-PDZ protein; PMCA-interacting single-PDZ protein |
| Protein Family: | PDZ domain-containing protein |
| UniProt Gene Name: | PDZD11�� |
| UniProt Entry Name: |
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