Human PDCL3 Recombinant Protein (RPPB4214)
- SKU:
- RPPB4214
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q9H2J4
Frequently bought together:
Description
| Product Name: | Human PDCL3 Recombinant Protein |
| Product Code: | RPPB4214 |
| Size: | 20µg |
| Species: | Human |
| Target: | PDCL3 |
| Synonyms: | Phosducin-like protein 3, VIAF1, Viral IAP-associated factor 1, HTPHLP, VIAF-1, PHLP3, PHLP2A, IAP-associated factor VIAF1. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The PDCL3 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 100mM NaCl and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMQDPNAD TEWNDILRKK GILPPKESLK ELEEEAEEEQ RILQQSVVKT YEDMTLEELE DHEDEFNEED ERAIEMYRRR RLAEWKATKL KNKFGEVLEI SGKDYVQEVT KAGEGLWVIL HLYKQGIPLC ALINQHLSGL ARKFPDVKFI KAISTTCIPN YPDRNLPTIF VYLEGDIKAQ FIGPLVFGGM NLTRDELEWK LSESGAIMTD LEENPKKPIE DVLLSSVRRS VLMKRDSDSE GD |
PDCL3 belongs to the phosducin-like protein family which its members are known to bind to the beta-gamma subunits of G proteins. PDCL3 is a potential regulator of heterotrimeric G proteins and has a large amino acid sequence homology with phosducin.
PDCL3 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 262 amino acids (1-239) and having a molecular mass of 30.0kDa.PDCL3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | PDCL3: Modulates the activation of caspases during apoptosis. Is a substrate for Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV) IAP-mediated ubiquitination. Belongs to the phosducin family.Protein type: ApoptosisChromosomal Location of Human Ortholog: 2q11.2Cellular Component: cytoplasm; nucleusMolecular Function: protein binding; queuine tRNA-ribosyltransferase activityBiological Process: positive regulation of angiogenesis; positive regulation of endothelial cell proliferation; queuosine biosynthetic process; regulation of peptidyl-tyrosine phosphorylation |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the phosducin-like protein family and is a putative modulator of heterotrimeric G proteins. The protein shares extensive amino acid sequence homology with phosducin. Members of the phosducin-like protein family have been shown to bind to the beta-gamma subunits of G proteins. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9H2J4 |
| NCBI GenInfo Identifier: | 50401164 |
| NCBI Gene ID: | 79031 |
| NCBI Accession: | Q9H2J4.1 |
| UniProt Secondary Accession: | Q9H2J4,Q53S68, B2RA00 |
| UniProt Related Accession: | Q9H2J4 |
| Molecular Weight: | 27,614 Da |
| NCBI Full Name: | Phosducin-like protein 3 |
| NCBI Synonym Full Names: | phosducin like 3 |
| NCBI Official Symbol: | PDCL3�� |
| NCBI Official Synonym Symbols: | VIAF; PHLP3; VIAF1; HTPHLP; PHLP2A�� |
| NCBI Protein Information: | phosducin-like protein 3 |
| UniProt Protein Name: | Phosducin-like protein 3 |
| UniProt Synonym Protein Names: | HTPHLP; PhPL3; Viral IAP-associated factor 1; VIAF-1 |
| Protein Family: | Phosducin-like protein |
| UniProt Gene Name: | PDCL3�� |
| UniProt Entry Name: | PDCL3_HUMAN |
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