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Human PDCD1LG2 Recombinant Protein (RPPB4207)

SKU:
RPPB4207
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q9BQ51
€309
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Description

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Product Name:Human PDCD1LG2 Recombinant Protein
Product Code:RPPB4207
Size:25µg
Species:Human
Target:PDCD1LG2
Synonyms:Programmed cell death 1 ligand 2, PD-1 ligand 2, PD-L2, PDCD1 ligand 2, Programmed death ligand 2, PDCD1LG2, B7-DC, Butyrophilin B7-DC, CD273, B7DC, CD273, PDCD1L2, PDL2, bA574F11.2, Btdc.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered colorless solution.
Formulation:PDCD1LG2 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 0.4M Urea and 10% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSLFTVTVP KELYIIEHGS NVTLECNFDT GSHVNLGAIT ASLQKVENDT SPHRERATLL EEQLPLGKAS FHIPQVQVRD EGQYQCIIIY GVAWDYKYLT LKVKASYRKI NTHILKVPET DEVELTCQAT GYPLAEVSWP NVSVPANTSH SRTPEGLYQV TSVLRLKPPP GRNFSCVFWN THVR

Programmed cell death 1 ligand 2 (PDCD1LG2) which takes part in the costimulatory signal, is necessary for T-cell proliferation. PDCD1LG2 is also involved in IFNG production in a PDCD1-independent way. The interaction with PDCD1 inhibits T-cell proliferation by preventing cytokine production and cell cycle progression.

PDCD1LG2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 204 amino acids (20-200 a.a.) and having a molecular mass of 22.8kDa.PDCD1LG2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
UniProt Code:Q9BQ51
NCBI GenInfo Identifier:73917618
NCBI Gene ID:80380
NCBI Accession:Q9BQ51.2
UniProt Secondary Accession:Q9BQ51,Q14CN8, Q5T7Z6, Q6JXL8, Q6JXL9,
UniProt Related Accession:Q9BQ51
Molecular Weight:20,745 Da
NCBI Full Name:Programmed cell death 1 ligand 2
NCBI Synonym Full Names:programmed cell death 1 ligand 2
NCBI Official Symbol:PDCD1LG2��
NCBI Official Synonym Symbols:B7DC; Btdc; PDL2; CD273; PD-L2; PDCD1L2; bA574F11.2��
NCBI Protein Information:programmed cell death 1 ligand 2
UniProt Protein Name:Programmed cell death 1 ligand 2
UniProt Synonym Protein Names:Butyrophilin B7-DC; B7-DC; CD_antigen: CD273
Protein Family:Programmed cell death
UniProt Gene Name:PDCD1LG2��

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