Description
Product Name: | Nanodisc Human PACR-Strep Protein |
SKU: | HDFP1163 |
Size: | 10μg |
Target: | PACR |
Tag: | C-Flag&Strep Tag |
Expression Host: | HEK293 |
Conjugate: | Unconjugated |
Synonyms: | PAC1, PAC1R, PACAPR, PACAPRI |
Protein Families: | GPCR, Transmembrane, Druggable Genome. |
Protein Description: | Human PACR-Strep full length protein-synthetic nanodisc |
Protein Pathways: | GPCRDB Class B Secretin-like, Cancer, Neurotrophin & Receptors. |
Molecular Weight: | The human full length PACR-Strep protein has a MW of 53.3 kDa |
This gene encodes type I adenylate cyclase activating polypeptide receptor, which is a membrane-associated protein and shares significant homology with members of the glucagon/secretin receptor family. This receptor mediates diverse biological actions of adenylate cyclase activating polypeptide 1 and is positively coupled to adenylate cyclase. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2010]
Uniprot ID: | P41586 |
Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Usage: | Research use only |