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Human P-glycoRecombinant Protein1/ABCB1 Recombinant Protein (His tag) (RPES5621)

SKU:
RPES5621
Product Type:
Recombinant Protein
Species:
Human
€149

Description

Product Name:Human P-glycoRecombinant Protein1/ABCB1 Recombinant Protein (His tag)
Product Code:RPES5621
Size:20µg
Species:Human
Expression Host:E.coli
Synonyms:ATP-dependent translocase ABCB1, ABCB1, ATP-binding cassette sub-family B member 1, P-glycoprotein 1, Phospholipid transporter ABCB1, CD243,
Mol Mass:25.96 kDa
AP Mol Mass:32 kDa
Tag:N-His
Purity:> 95 % as determined by reducing SDS-PAGE.
Endotoxin Level:Please contact us for more information.
Bio Activity:Testing in progress
Sequence:Leu 392-Met 628
Accession:P08183
Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Formulation:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Reconstitution:Please refer to the printed manual for detailed information.
Background:Translocates drugs and phospholipids across the membrane (PubMed:8898203, PubMed:2897240, PubMed:9038218, PubMed:35970996). Catalyzes the flop of phospholipids from the cytoplasmic to the exoplasmic leaflet of the apical membrane. Participates mainly to the flop of phosphatidylcholine, phosphatidylethanolamine, beta-D-glucosylceramides and sphingomyelins (PubMed:8898203). Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells (PubMed:2897240, PubMed:9038218, PubMed:35970996).

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