Human ORAOV1 Recombinant Protein (RPPB4164)
- SKU:
- RPPB4164
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q8WV07
Description
| Product Name: | Human ORAOV1 Recombinant Protein |
| Product Code: | RPPB4164 |
| Size: | 10µg |
| Species: | Human |
| Target: | ORAOV1 |
| Synonyms: | Oral cancer-overexpressed protein 1, Tumor-amplified and overexpressed sequence 1, ORAOV1, TAOS1. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | ORAOV1 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.1M NaCl and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSHMAGSQD IFDAIVMADE RFHGEGYREG YEEGSSLGVM EGRQHGTLHG AKIGSEIGCY QGFAFAWKCL LHSCTTEKDS RKMKVLESLI GMIQKFPYDD PTYDKLHEDL DKIRGKFKQF CSLLNVQPDF KISAEGSGLS F |
Oral cancer-overexpressed protein 1 (ORAOV1) is a candidate oncogene in the 11q13 chromosomal region. Functional analyses showed that ORAOV1 was involved in the regulation of HeLa cell growth via its effect on cell cycle and apoptosis. ORAOV1 is widely expressed; it has a high expression in the placenta, kidney and skeletal muscle. ORAOV1 is amplified and overexpressed in oral cancer cells.
ORAOV1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 161 amino acids (1-137 a.a) and having a molecular mass of 17.9kDa.ORAOV1 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | ORAOV1: Belongs to the ORAOV1 family.Protein type: Unknown functionChromosomal Location of Human Ortholog: 11q13.3Biological Process: ribosomal large subunit biogenesis and assembly |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8WV07 |
| NCBI GenInfo Identifier: | 85701377 |
| NCBI Gene ID: | 220064 |
| NCBI Accession: | Q8WV07.2 |
| UniProt Secondary Accession: | Q8WV07,Q8NFK0, B2R4R2 |
| UniProt Related Accession: | Q8WV07 |
| Molecular Weight: | 15,354 Da |
| NCBI Full Name: | Oral cancer-overexpressed protein 1 |
| NCBI Synonym Full Names: | oral cancer overexpressed 1 |
| NCBI Official Symbol: | ORAOV1�� |
| NCBI Official Synonym Symbols: | TAOS1�� |
| NCBI Protein Information: | oral cancer-overexpressed protein 1 |
| UniProt Protein Name: | Oral cancer-overexpressed protein 1 |
| UniProt Synonym Protein Names: | Tumor-amplified and overexpressed sequence 1 |
| Protein Family: | Oral cancer-overexpressed protein |
| UniProt Gene Name: | ORAOV1�� |
| UniProt Entry Name: | ORAV1_HUMAN |
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