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Human MREG Recombinant Protein (RPPB3996)

SKU:
RPPB3996
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q8N565
$371
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Description

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Product Name:Human MREG Recombinant Protein
Product Code:RPPB3996
Size:10µg
Species:Human
Target:MREG
Synonyms:Melanoregulin, DSU, Dilute Suppressor Protein Homolog, WDT2,Whn-Dependent Transcript 2.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered clear solution.
Formulation:MREG protein solution (0.5mg/ml) containing 20mM Tris-HClbuffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.
Purity:Greaterthan 90% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMGLRDWL RTVCCCCGCE CLEERALPEK EPLVSDNNPY SSFGATLVRDDEKNLWSMPH DVSHTEADDD RTLYNLIVIR NQQAKDSEEW QKLNYDIHTL RQVRREVRNR WKCILEDLGFQKEADSLLSV TKLSTISDSK NTRKAREMLL KLAEETNIFP TSWELSERYL FVVDRLIALD AAEEFFKLARRTYPKKPGVP CLADGQKELH YLPFPSP

Melanoregulin(MREG) takes part in membrane fusion and in regulating the biogenesis of diskmembranes of photoreceptor rods. MREG is expressed in photoreceptor cells astwo isoforms as a result of alternative splicing. MREG interacts withPeripherin-2, a photoreceptor specific tetraspanin protein which is required topreserve normal cell structure during the renewal process of membrane fusion.Moreover, MREG plays a part in the incorporation of pigments into hair.

MREG Human Recombinant produced in E.Coli is a single,non-glycosylated polypeptide chain containing 237 amino acids (1-214 a.a) andhaving a molecular mass of 27.3kDa.MREG is fused to a 23 amino acid His-tag at N-terminus& purified by proprietary chromatographic techniques.

UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q8N565
NCBI GenInfo Identifier:124487399
NCBI Gene ID:55686
NCBI Accession:NP_060470.2
UniProt Secondary Accession:Q8N565,Q53R89, Q53TC1, Q5XKB6, Q9NWC9, Q9P1S1
UniProt Related Accession:Q8N565
Molecular Weight:26,044 Da
NCBI Full Name:melanoregulin
NCBI Synonym Full Names:melanoregulin
NCBI Official Symbol:MREG��
NCBI Official Synonym Symbols:DSU; WDT2��
NCBI Protein Information:melanoregulin; dilute suppressor protein homolog; whn-dependent transcript 2
UniProt Protein Name:Melanoregulin
UniProt Synonym Protein Names:Dilute suppressor protein homolog
Protein Family:
UniProt Gene Name:MREG��
UniProt Entry Name:MREG_HUMAN

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