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PE/Cyanine5 Anti-Human/Mouse/Rat CD47 Antibody [MIAP410] (AGEL0683)

SKU:
AGEL0683
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Applications:
FC
€219 - €519
Frequently bought together:

Description

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PE/Cyanine5 Anti-Human/Mouse/Rat CD47 Antibody [MIAP410]

The CD47 Monoclonal Antibody (MIAP410) is a crucial tool for researchers studying the CD47 protein in human, mouse, and rat samples. This PE-Cyanine5 conjugated antibody, catalog number AGEL0683, is specifically designed for flow cytometry applications, enabling precise and efficient detection of CD47 in a variety of cell types.CD47, also known as integrin-associated protein, plays a key role in immune regulation and cell signaling processes. It is involved in the modulation of cell migration, phagocytosis, and apoptosis, making it a significant target for research in immunology, cancer biology, and other fields. Understanding the function and expression of CD47 is essential for unraveling its role in various physiological and pathological processes.

By utilizing the CD47 Monoclonal Antibody (MIAP410) in flow cytometry experiments, researchers can gain valuable insights into the expression levels and localization of CD47 in different cell populations. This antibody's high specificity and sensitivity ensure reliable results, making it an indispensable tool for investigating the biology of CD47 and its implications in health and disease.Overall, the CD47 Monoclonal Antibody (MIAP410) offers researchers a powerful instrument for studying the intricate mechanisms involving CD47 in human, mouse, and rat samples, paving the way for advancements in the understanding of immune regulation, cancer progression, and therapeutic development.

Product Title:PE/Cyanine5 Anti-Human/Mouse/Rat CD47 Antibody [MIAP410]
SKU:AGEL0683
Size:25µg, 100µg
Clone No:MIAP410
Synonyms:Leukocyte surface antigen CD47;Cd47;Integrin-associated protein;IAP;
Host Species:Mouse
Reactivity:Human;Mouse;Rat
Application:FCM
Isotype:Mouse IgG1, κ
Form:Liquid
Conjugation:PE/Cyanine 5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:Q08722 Q61735 P97829
Gene ID:961,16423,29364
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPα, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking.

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