PE/Cyanine5.5 Anti-Human/Mouse/Rat CD47 Antibody [MIAP410] (AGEL0675)
- SKU:
- AGEL0675
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Applications:
- FC
Frequently bought together:
Description
Product Title: | PE/Cyanine5.5 Anti-Human/Mouse/Rat CD47 Antibody [MIAP410] |
SKU: | AGEL0675 |
Size: | 20 Tests, 100 Tests, 200 Tests |
Clone No: | MIAP410 |
Synonyms: | Leukocyte surface antigen CD47;Cd47;Integrin-associated protein;IAP; |
Host Species: | Mouse |
Reactivity: | Human;Mouse;Rat |
Application: | FCM |
Isotype: | Mouse IgG1, κ |
Isotype Control: | PE/Cyanine5.5 Mouse IgG1, κ Isotype Control[MOPC-21] |
Form: | Liquid |
Conjugation: | PE/Cyanine 5.5 |
Recommended Use: | Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. |
Spectrum: |
Swissprot: | Q08722 Q61735 P97829 |
Gene ID: | 961,16423,29364 |
Storage Buffer: | Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant. |
Stability & Storage: | Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase. |
Background: | CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPα, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking. |