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PE/Cyanine5.5 Anti-Human/Mouse/Rat CD47 Antibody [MIAP410] (AGEL0675)

SKU:
AGEL0675
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Applications:
FC
$311 - $1,067
Frequently bought together:

Description

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PE/Cyanine5.5 Anti-Human/Mouse/Rat CD47 Antibody [MIAP410]

The CD47 Monoclonal Antibody (PE/Cyanine5.5 Conjugated) (MIAP410) is a cutting-edge tool for researchers studying CD47, a crucial cell surface protein with diverse functions in immune regulation and cancer biology. This advanced antibody, conjugated with PE/Cyanine5.5 for fluorescent detection, specifically targets CD47 in human, mouse, and rat samples.CD47, also known as integrin-associated protein (IAP), plays a pivotal role in immune evasion and self-recognition processes, making it a key player in cancer progression and immunotherapy. By targeting CD47, researchers can gain insights into mechanisms underlying tumor immune escape and develop novel strategies for cancer treatment.The validated reactivity of the MIAP410 antibody with CD47 makes it an indispensable tool for flow cytometry and immunofluorescence assays, enabling precise detection and characterization of CD47 expression levels in various cell types and tissues.

By utilizing this state-of-the-art antibody, scientists can delve deeper into the complex interplay between CD47 and the immune system, paving the way for innovative therapeutic interventions in cancer and other immune-related disorders.For researchers seeking high-quality reagents to advance their studies in immunology, oncology, and beyond, the CD47 Monoclonal Antibody (PE/Cyanine5.5 Conjugated) (MIAP410) from AssayGenie (AGEL0675) provides a valuable solution for exploring the multifaceted roles of CD47 in health and disease.

Product Title:PE/Cyanine5.5 Anti-Human/Mouse/Rat CD47 Antibody [MIAP410]
SKU:AGEL0675
Size:20 Tests, 100 Tests, 200 Tests
Clone No:MIAP410
Synonyms:Leukocyte surface antigen CD47;Cd47;Integrin-associated protein;IAP;
Host Species:Mouse
Reactivity:Human;Mouse;Rat
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE/Cyanine5.5 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:Q08722 Q61735 P97829
Gene ID:961,16423,29364
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD47, also known as Integrin-Associated Protein (IAP), is a membrane protein of about 50 kD with an IgV-like extracelluluar domain, a five membrane-spanning segment and a short terminal cytoplasmic region. It is widely expressed on many cell types and often associated with beta 3 integrins. It has been reported that CD47 functions as a self marker. Red cells lacking CD47 were rapidly cleared from the bloodstream by splenic macrophages. By binding to SIRPα, CD47 controls hemostatic innate immune functions, such as phagocytosis and cell trafficking.

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