Human MMP3 Recombinant Protein (His tag)
- SKU:
- RPES5996
- Product Type:
- Recombinant Protein
- Species:
- Human
Frequently bought together:
Description
Product Name: | Human MMP3 Recombinant Protein (His tag) |
Product Code: | RPES5996 |
Size: | 20µg |
Species: | Human |
Expression Host: | HEK293 Cells |
Synonyms: | Stromelysin-1, SL-1, Matrix metalloproteinase-3, Transin-1, MMP3, STMY1, CHDS6, MMP-3, SL-1, STMY, STR1 |
Mol Mass: | 52.36 kDa |
AP Mol Mass: | 59 kDa |
Tag: | C-His |
Purity: | > 95 % as determined by reducing SDS-PAGE. |
Endotoxin Level: | Please contact us for more information. |
Bio Activity: | Testing in progress |
Sequence: | Met1-Cys477 |
Accession: | P08254 |
Storage: | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months. |
Shipping: | This product is provided as lyophilized powder which is shipped with ice packs. |
Formulation: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual. |
Reconstitution: | Please refer to the printed manual for detailed information. |
Background: | MMP3 is a member of the matrix metalloproteinase (MMP) family whose members are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, tissue remodeling, and disease processes including arthritis and metastasis. The MMP-3 enzyme degrades collagen types II, III, IV, IX, and X, proteoglycans, fibronectin, laminin, and elastin. In addition, MMP-3 can also activate other MMPs such as MMP-1, MMP-7, and MMP-9, rendering MMP-3 crucial in connective tissue remodeling.[3] The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. |