Human MASP2 Recombinant Protein (hFc Tag) (HDPT0172)
- SKU:
- HDPT0172
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immune Checkpoint
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Description
Human MASP2 Recombinant Protein (hFc Tag)
| Description: | This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is proteolytically processed to generate A and B chains that heterodimerize to form the mature protease. This protease cleaves complement components C2 and C4 in order to generate C3 convertase in the lectin pathway of the complement system. The encoded protease also plays a role in the coagulation cascade through cleavage of prothrombin to form thrombin. Myocardial infarction and acute stroke patients exhibit reduced serum concentrations of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. |
| Product name: | Human MASP2 Recombinant Protein (hFc Tag) |
| Synonyms: | MAP19, MASP-2, MASP1P1, sMAP |
| Type: | protein |
| Size: | 50 µg |
| Name: | MASP2 |
| Origin: | Human |
| Source: | HEK293 |
| Protein Type: | Recombinant |
| Application: | Contact Technical Support |
| Purity: | > 90% |
| Purification: | affinity purification |
| Format: | Lyophilized |
| Conjugate: | N-Human Fc tag |
| Storage: | Store at -80°C for 12 months (Avoid repeated freezing and thawing) |
| Usage: | Research use only |
| Buffer: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. |
| Reconstitution: | Reconstitute with deionized water |
| Sequence: | hFc（Glu99-Ala330）+MASP2 （Gln298-Ser684） |
| Gene ID: | 10747 |
| Uniprot: | O00187 |
| Molecular Weight: | 68.4 kDa |
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