Human LT4R2 full length protein-synthetic nanodisc (HDFP333)
- SKU:
- HDFP333
- Size:
- 10μg
- Target:
- LT4R2
- Tag:
- C-Flag Tag
- Expression Host:
- HEK293
- Conjugate:
- Unconjugated
Description
| Product Name: | Nanodisc Human LT4R2 Protein |
| SKU: | HDFP333 |
| Size: | 10μg |
| Target: | LT4R2 |
| Tag: | C-Flag Tag |
| Expression Host: | HEK293 |
| Conjugate: | Unconjugated |
| Synonyms: | BLT2, BLTR2, JULF2, KPG_004, LTB4-R 2, LTB4-R2, NOP9 |
| Protein Families: | GPCR, Transmembrane, Druggable Genome. |
| Protein Description: | Human LT4R2 full length protein-synthetic nanodisc |
| Protein Pathways: | GPCRDB Other, Asthma, Autoimmune & Inflammatory Response. |
| Molecular Weight: | The human full length LT4R2 protein has a MW of 37.9kDa |
Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3.[UniProtKB/Swiss-Prot Function]
| Uniprot ID: | Q9NPC1 |
| Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Usage: | Research use only |
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