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Human LRRC59 Recombinant Protein (RPPB3878)

SKU:
RPPB3878
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q96AG4
$371
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Description

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Product Name:Human LRRC59 Recombinant Protein
Product Code:RPPB3878
Size:10µg
Species:Human
Target:LRRC59
Synonyms:Leucine Rich Repeat Containing 59, Ribosome-Binding Protein P34, p34, Leucine-Rich Repeat-Containing Protein 59.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered clear solution.
Formulation:The LRRC59 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 0.2M NaCl, 2mM DTT, 2mM EDTA and 50% glycerol.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 90.0% as determined by SDS-PAGE.
Amino Acid Sequence:MGSSHHHHHH SSGLVPRGSH MGSMTKAGSK GGNLRDKLDG NELDLSLSDL NEVPVKELAA LPKATILDLS CNKLTTLPSD FCGLTHLVKL DLSKNKLQQL PADFGRLVNL QHLDLLNNKL VTLPVSFAQL KNLKWLDLKD NPLDPVLAKV AGDCLDEKQC KQCANKVLQH MKAVQADQER ERQRRLEVER EAEKKREAKQ RAKEAQEREL RKREKAEEKE RRRKEYDALK AAKREQEKKP KKEANQAPKS KSGSRPRKPP PRKHTRS

LRRC59 controls nuclear import of exogenous FGF1 by enabling interaction with the nuclear import mechanism and by transporting cytosolic FGF1 to and through the nuclear pores. LRRC59 is essential for nuclear import of FGF1, but not that of FGF2.

LRRC59 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 267 amino acids (1-244) and having a molecular mass of 30.3kDa.LRRC59 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:LRRC59: Interacts with SGOL1.
UniProt Protein Details:

Protein type:Membrane protein, integral

Chromosomal Location of Human Ortholog: 17q21.33

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; membrane; nuclear envelope

UniProt Code:Q96AG4
NCBI GenInfo Identifier:40254924
NCBI Gene ID:55379
NCBI Accession:NP_060979.2
UniProt Secondary Accession:Q96AG4,Q9P189, B2RE83, D3DTX8,
UniProt Related Accession:Q96AG4
Molecular Weight:Calculated MW: 35kDaMolecular Weight: 307
NCBI Full Name:leucine-rich repeat-containing protein 59
NCBI Synonym Full Names:leucine rich repeat containing 59
NCBI Official Symbol:LRRC59��
NCBI Official Synonym Symbols:p34; PRO1855��
NCBI Protein Information:leucine-rich repeat-containing protein 59
UniProt Protein Name:Leucine-rich repeat-containing protein 59
UniProt Synonym Protein Names:Ribosome-binding protein p34; p34
Protein Family:Leucine-rich repeat-containing protein
UniProt Gene Name:LRRC59��
UniProt Entry Name:LRC59_HUMAN

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