Human LGR5 Full-Length Bioactive Membrane Protein (HDFP054)
- SKU:
- HDFP054
- Product Type:
- Recombinant Protein
- Protein Type:
- Full-Length Bioactive Membrane Protein
- Species:
- Human
- Uniprot:
- O75473
Description
system_update_altDatasheet
| Product name | Human LGR5 full length protein-synthetic nanodisc |
| Size: | 10ug |
| Product SKU: | HDFP054 |
| Product Category | Full Length Transmembrane Proteins |
| Target: | LGR5 |
| Uniprot: | O75473 |
| Description: | Human LGR5 full length protein-synthetic nanodisc |
| Molecular Weight: | The human full length LGR5 protein has a MW of 100.0 kDa |
| Protein Family: | Druggable Genome, GPCR, Transmembrane |
| Protein Pathways: | |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Synonyms: | FEX; GPR49; GPR67; GRP49; HG38 |
| Expression System: | HEK293 |
| Formulation: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| Background: | The protein is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene. |
| Delivery: | In Stock |
| Usage | Research use only |
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