Human LDOC1L Recombinant Protein (RPPB3853)
- SKU:
- RPPB3853
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q6ICC9
Description
Product Name: | Human LDOC1L Recombinant Protein |
Product Code: | RPPB3853 |
Size: | 20µg |
Species: | Human |
Target: | LDOC1L |
Synonyms: | Protein LDOC1L, Leucine zipper protein down-regulated in cancer cells-like, Mammalian retrotransposon-derived protein 6, LDOC1L, MAR6, MART6, dJ1033E15.2. |
Source: | Escherichia Coli |
Physical Appearance: | Sterile filtered colorless solution. |
Formulation: | LDOC1L protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.1M NaCl, 40% glycerol, 2mM DTT, 0.1mM PMSF and 1mM EDTA. |
Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
Purity: | Greater than 90% as determined by SDS-PAGE. |
Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSHMVQPQT SKAESPALAA SPNAQMDDVI DTLTSLRLTN SALRREASTL RAEKANLTNM LESVMAELTL LRTRARIPGA LQITPPISSI TSNGTRPMTT PPTSLPEPFS GDPGRLAGFL MQMDRFMIFQ ASRFPGEAER VAFLVSRLTG EAEKWAIPHM QPDSPLRNNY QGFLAELRRT YKSPLRHARR AQIRKTSASN RAVRERQMLC RQLASAGTGP CPVHPASNGT SPAPALPARA RNL |
Leucine zipper down-regulated in cancer 1-like (LDOC1L) is a member of the LDOC1 family. LDOC1L is a nuclear protein containing a leucine zipper-like motif and a proline-rich region that shares noticeable similarity with an SH3-binding domain. LDOC1L localizes to the nucleus and is downregulated in certain cancer cell lines. LDOC1L is believed to regulate the transcriptional response mediated by the nuclear factor kB (NFkB).
LDOC1L Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 263 amino acids (1-239 a.a) and having a molecular mass of 28.7kDa.LDOC1L is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
UniProt Protein Function: | LDOC1L iso3: |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 22q13.31 |
UniProt Code: | Q6ICC9 |
NCBI GenInfo Identifier: | 74762303 |
NCBI Gene ID: | 84247 |
NCBI Accession: | Q6ICC9.1 |
UniProt Secondary Accession: | Q6ICC9,Q6ZTR1, |
UniProt Related Accession: | Q6ICC9 |
Molecular Weight: | 26,154 Da |
NCBI Full Name: | Protein LDOC1L |
NCBI Synonym Full Names: | leucine zipper down-regulated in cancer 1 like |
NCBI Official Symbol: | LDOC1L�� |
NCBI Official Synonym Symbols: | Mar6; Mart6; dJ1033E15.2�� |
NCBI Protein Information: | protein LDOC1L |
UniProt Protein Name: | Protein LDOC1L |
UniProt Synonym Protein Names: | Leucine zipper protein down-regulated in cancer cells-like; Mammalian retrotransposon-derived protein 6 |
Protein Family: | Protein |
UniProt Gene Name: | LDOC1L�� |
UniProt Entry Name: | LDOCL_HUMAN |