Human KLF3 Recombinant Protein (RPPB3793)
- SKU:
- RPPB3793
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- P57682
Description
| Product Name: | Human KLF3 Recombinant Protein |
| Product Code: | RPPB3793 |
| Size: | 20µg |
| Species: | Human |
| Target: | KLF3 |
| Synonyms: | ATP Synthase H+ Transporting, Mitochondrial Fo Complex Subunit D, ATP Synthase D Chain Mitochondrial, ATP Synthase H+ Transporting Mitochondrial F1F0 Subunit D, ATPase Subunit D, My032 Protein, ATPQ. Kruppel-Like Factor 3 (Basic), CACCC-Box-Binding Protein BKLF , Basic Kruppel Like Factor, Krueppel-Like Factor 3, Transcript Ch138, BKLF, TEF-2. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile filtered colorless solution. |
| Formulation: | The KLF3 solution contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks.�Store, frozen at -20°C for longer periods of time.�For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMLMFDPV PVKQEAMDPV SVSYPSNYME SMKPNKYGVI YSTPLPEKFF QTPEGLSHGI QMEPVDLTVN KRSSPPSAGN SPSSLKFPSS HRRASPGLSM PSSSPPIKKY SPPSPGVQPF GVPLSMPPVM AAALSRHGIR SPGILPVIQP VVVQPVPFMY TSHLQQPLMV SLSEEMENSS SSMQVPVIES YEKPISQKKI KIEPGIEPQR TDYYPEEMSP PLMNSVSPPQ ALLQENHPSV IVQPGKRPLP VESPDTQRKR RIHRCDYDGC NKVYTKSSHL KAHRRTHTGE KPYKCTWEGC TWKFARSDEL TRHFRKHTGI KPFQCPDCDR SFSRSDHLAL HRKRHMLV |
KLF3 belongs to the Sp1-like/KLF family. KLFs is a family of evolutionarily conserved zinc finger-having transcription factors with various regulatory purposes in cell growth, embryogenesis, proliferation and differentiation. KLF3 is Kruppel-like zinc finger which contain transcription factors and take part in hematopoiesis.
KLF3 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 368 amino acids (1-345) and having a molecular mass of 41.2kDa.KLF3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | KLF3: Binds to the CACCC box of erythroid cell-expressed genes. May play a role in hematopoiesis. Belongs to the krueppel C2H2-type zinc-finger protein family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Transcription factor; C2H2-type zinc finger protein; DNA-binding Chromosomal Location of Human Ortholog: 4p14 Cellular Component: nucleus Molecular Function:DNA binding; metal ion binding; transcription factor activity Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent; multicellular organismal development |
| UniProt Code: | P57682 |
| NCBI GenInfo Identifier: | 12644533 |
| NCBI Gene ID: | 51274 |
| NCBI Accession: | P57682.1 |
| UniProt Secondary Accession: | P57682,Q6PIR1, Q86TN0, Q9P2X6, |
| UniProt Related Accession: | P57682 |
| Molecular Weight: | 25,430 Da |
| NCBI Full Name: | Krueppel-like factor 3 |
| NCBI Synonym Full Names: | Kruppel-like factor 3 (basic) |
| NCBI Official Symbol: | KLF3�� |
| NCBI Official Synonym Symbols: | BKLF�� |
| NCBI Protein Information: | Krueppel-like factor 3; TEF-2; transcript ch138; basic Kruppel-like factor; basic kruppel like factor; basic krueppel-like factor; CACCC-box-binding protein BKLF |
| UniProt Protein Name: | Krueppel-like factor 3 |
| UniProt Synonym Protein Names: | Basic krueppel-like factor; CACCC-box-binding protein BKLF; TEF-2 |
| Protein Family: | Krueppel-like factor |
| UniProt Gene Name: | KLF3�� |
| UniProt Entry Name: | KLF3_HUMAN |
