Description
Product Name: | Nanodisc Human KCMB1-Strep Protein |
SKU: | HDFP1261 |
Size: | 10μg |
Target: | KCMB1 |
Tag: | C-Flag&Strep Tag |
Expression Host: | HEK293 |
Conjugate: | Unconjugated |
Synonyms: | BKbeta1, K(VCA)beta, SLO-BETA, hbeta1, hslo-beta, k(VCA)beta-1, slo-beta-1 |
Protein Families: | Ion Channels: Other. |
Protein Description: | Human KCMB1-Strep full length protein-synthetic nanodisc |
Molecular Weight: | The human full length KCMB1-Strep protein has a MW of 21.8 kDa |
MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the product of this gene, the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. [provided by RefSeq, Jul 2008]
Uniprot ID: | Q16558 |
Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Usage: | Research use only |