Human IL5RA Recombinant Protein (hFc Tag) (HDPT0183)
- SKU:
- HDPT0183
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immune Checkpoint
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Description
Human IL5RA Recombinant Protein (hFc Tag)
| Description: | The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported. |
| Product name: | Human IL5RA Recombinant Protein (hFc Tag) |
| Synonyms: | IL5Ra,CD125,IL-5 R alpha |
| Type: | protein |
| Size: | 50 µg |
| Name: | IL5 |
| Origin: | Human |
| Source: | HEK293 |
| Protein Type: | Recombinant |
| Application: | Contact Technical Support |
| Purity: | > 90% |
| Purification: | affinity purification |
| Format: | Lyophilized |
| Conjugate: | C-Human Fc tag |
| Storage: | Store at -80°C for 12 months (Avoid repeated freezing and thawing) |
| Usage: | Research use only |
| Buffer: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. |
| Reconstitution: | Reconstitute with deionized water |
| Sequence: | IL5RA（Asp21-Pro338）+hFc（Glu99-Ala330） |
| Gene ID: | 3567 |
| Uniprot: | Q01344 |
| Molecular Weight: | 70-100 kDa |
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