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Human IL-5 Polyclonal Antibody (CAB21170)

SKU:
CAB21170
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Mouse
Rat
Applications:
WB
Isotype:
IgG
Host Species:
Rabbit
$167 - $503
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Human IL-5 Polyclonal Antibody
SKU:CAB21170
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat,Other (Wide Range Predicted)
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 20-134 of human IL-5 (NP_000870.1).
Sequence:IPTE IPTS ALVK ETLA LLST HRTL LIAN ETLR IPVP VHKN HQLC TEEI FQGI GTLE SQTV QGGT VERL FKNL SLIK KYID GQKK KCGE ERRR VNQF LDYL QEFL GVMN TEWI IES
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:EDF; TRF; IL-5; Human IL-5
Positive Sample:Recombinant Human IL-5 Protein
Conjugate:Unconjugated
Cellular Localization:Secreted.
Calculated MW:15kDa
Observed MW:18-23kDa

This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.

Purification Method:Affinity purification
Gene ID:3567
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of recombinant Human IL-5 Protein, using Human IL-5 Rabbit pAb (CAB21170) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 10ng/5ng per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 0.8s.

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