Human IL-5 Polyclonal Antibody (CAB21170)
- SKU:
- CAB21170
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Applications:
- WB
- Isotype:
- IgG
- Host Species:
- Rabbit
Description
Product Name: | Human IL-5 Polyclonal Antibody |
SKU: | CAB21170 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat,Other (Wide Range Predicted) |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-134 of human IL-5 (NP_000870.1). |
Sequence: | IPTE IPTS ALVK ETLA LLST HRTL LIAN ETLR IPVP VHKN HQLC TEEI FQGI GTLE SQTV QGGT VERL FKNL SLIK KYID GQKK KCGE ERRR VNQF LDYL QEFL GVMN TEWI IES |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | EDF; TRF; IL-5; Human IL-5 |
Positive Sample: | Recombinant Human IL-5 Protein |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 15kDa |
Observed MW: | 18-23kDa |
This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.
Purification Method: | Affinity purification |
Gene ID: | 3567 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |