The Human IL-10 Monoclonal Antibody (PE Conjugated) JES3-9D7 (AGEL2033) is a powerful tool for researchers studying interleukin-10 (IL-10), a cytokine with potent anti-inflammatory properties. This monoclonal antibody, conjugated with phycoerythrin (PE), specifically targets IL-10 in human samples, enabling precise detection and quantification in flow cytometry and other immunological assays.IL-10 is a key regulator of immune responses, acting to dampen inflammation and promote immune tolerance. Dysregulation of IL-10 has been implicated in various disease states, including autoimmune disorders, inflammatory conditions, and infections.
By targeting IL-10 with JES3-9D7 (AGEL2033), researchers can gain insights into the role of this cytokine in different pathological processes and potentially identify new therapeutic targets for immune-related diseases.This high-quality monoclonal antibody offers specificity and sensitivity in detecting IL-10, making it an essential tool for studies in immunology, inflammation, and disease research. By utilizing JES3-9D7 (AGEL2033), researchers can further explore the complex functions of IL-10 and its impact on immune modulation, paving the way for novel treatment strategies and therapeutic interventions.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P22301
Gene ID:
3586
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
IL-10 was originally described as Cytokine Synthesis Inhibitory Factor (CSIF) by virtue of its ability to inhibit cytokine production by Th1 clones. IL-10 shares over 80% sequence homology with the Epstein-Barr virus protein BCRFI. The biological activities of IL-10 include inhibition of macrophage-mediated cytokine synthesis, suppression of the delayed type hypersensitivity response, and stimulation of the Th2 cell response, which results in elevated antibody production.