The Human IL-10 Monoclonal Antibody APC Conjugated (JES3-9D7) from Assay Genie (Catalog No. AGEL2034) is a powerful tool for researchers studying interleukin 10 (IL-10), a key cytokine involved in regulating immune responses. This monoclonal antibody specifically targets human IL-10 and is conjugated with APC for enhanced detection capabilities in flow cytometry and other fluorescent-based assays.IL-10 is a critical anti-inflammatory cytokine that plays a key role in immune regulation, suppressing inflammatory responses and promoting immune tolerance. Dysregulation of IL-10 has been implicated in various diseases, including autoimmune disorders, inflammatory conditions, and cancer.
The JES3-9D7 antibody enables precise detection and quantification of IL-10 in human samples, making it an invaluable asset for research in immunology, oncology, and related fields.With its high specificity and sensitivity, the Human IL-10 Monoclonal Antibody APC Conjugated (JES3-9D7) offers researchers a reliable tool for investigating the role of IL-10 in health and disease. Whether studying immune cell subsets, cytokine signaling pathways, or therapeutic interventions targeting IL-10, this antibody provides accurate and reproducible results to advance your research efforts.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P22301
Gene ID:
3586
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
IL-10 was originally described as Cytokine Synthesis Inhibitory Factor (CSIF) by virtue of its ability to inhibit cytokine production by Th1 clones. IL-10 shares over 80% sequence homology with the Epstein-Barr virus protein BCRFI. The biological activities of IL-10 include inhibition of macrophage-mediated cytokine synthesis, suppression of the delayed type hypersensitivity response, and stimulation of the Th2 cell response, which results in elevated antibody production.