Human IGF-1R Recombinant Protein (hFc Tag) (HDPT0214)
- SKU:
- HDPT0214
- Product Type:
- Recombinant Protein
- Species:
- Human
- Research Area:
- Immune Checkpoint
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Description
Human IGF-1R Recombinant Protein (hFc Tag)
| Description: | This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
| Product name: | Human IGF-1R Recombinant Protein (hFc Tag) |
| Synonyms: | IGF1R,IGFR,JTK13,CD221,MGC142170,MGC142172,MGC18216 |
| Type: | protein |
| Size: | 50 µg |
| Name: | IGF-1R |
| Origin: | Human |
| Source: | HEK293 |
| Protein Type: | Recombinant |
| Application: | Contact Technical Support |
| Purity: | Contact Technical Support |
| Purification: | affinity purification |
| Format: | Lyophilized |
| Conjugate: | C-Human Fc |
| Storage: | Store at -80°C for 12 months (Avoid repeated freezing and thawing) |
| Usage: | Research use only |
| Buffer: | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. |
| Reconstitution: | Reconstitute with deionized water |
| Sequence: | IGF-1R(Glu31-Asn932)+hFc(Glu99-Ala330) |
| Gene ID: | |
| Uniprot: | P08069 |
| Molecular Weight: | 124.74 kDa |
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