The Human HLA-DR Monoclonal Antibody (PERCP-Cyanine5.5 Conjugated) L243 (AGEL1398) is a cutting-edge tool for researchers delving into the intricacies of the human immune system. This monoclonal antibody, labeled with PERCP-Cyanine5.5 for fluorescent detection, targets the HLA-DR protein complex, a key component in antigen presentation.The HLA-DR proteins play a crucial role in immune recognition and activation, essential for the body's defense against pathogens and foreign invaders. The L243 antibody, meticulously developed and validated for specificity and sensitivity, enables precise and reliable detection of HLA-DR in human samples, making it a valuable asset in immunology research.
With its potential applications in flow cytometry, immunofluorescence, and other immunological techniques, the HLA-DR Monoclonal Antibody opens up new possibilities for investigating immune responses, autoimmunity, infectious diseases, and transplantation. Researchers aiming to deepen their understanding of the human immune system and its intricate mechanisms will find the L243 antibody to be an indispensable tool in their quest for knowledge and discovery.
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P01903 P01911
Gene ID:
3122,3123
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kD α (heavy) chain and a 27 kD β (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells.