The HLA-A/B/C Monoclonal Antibody (APC Conjugated, W6/32, AGEL1616) is a specialized antibody designed for use in research applications related to human leukocyte antigen (HLA) proteins. These monoclonal antibodies are specifically conjugated with allophycocyanin (APC) to facilitate multi-color flow cytometry analysis and cell sorting techniques.HLA molecules are essential components of the immune system, responsible for presenting antigens to T cells and regulating immune responses. The W6/32 antibody targets the HLA-A, HLA-B, and HLA-C antigens, allowing for precise identification and characterization of these proteins in various cell types and tissues.With its high specificity and sensitivity, the APC-conjugated HLA-A/B/C monoclonal antibody is a valuable tool for studies focusing on antigen presentation, immune response modulation, transplantation immunology, and disease pathogenesis.
Researchers can utilize this antibody to investigate HLA expression patterns, monitor immune cell activation, and explore HLA-associated diseases such as autoimmune disorders and viral infections.By incorporating the HLA-A/B/C monoclonal antibody (APC conjugated) into their experimental workflows, scientists can gain valuable insights into the complex mechanisms underlying immune recognition and immune-related disorders, paving the way for advancements in personalized medicine and immunotherapy strategies.
Product Title:
APC Anti-Human HLA-A,B,C Antibody [W6/32]
SKU:
AGEL1616
Size:
20 Tests, 100 Tests, 200 Tests
Clone No:
W6/32
Synonyms:
Major Histocompatibility Class I; MHC class I;
Host Species:
Mouse
Reactivity:
Human
Application:
FCM
Isotype:
Mouse IgG2a, κ
Isotype Control:
APC Mouse IgG2a, κ Isotype Control[C1.18.4]
Form:
Liquid
Conjugation:
APC
Recommended Use:
Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:
Swissprot:
P04439 P01889 P10321
Gene ID:
3105
Storage Buffer:
Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:
Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:
MHC class I antigens associated with β2-microglobulin are expressed by all human nucleated cells. MHC class I molecules are involved in presentation of antigens to CD8+ T cells. They play an important role in cell-mediated immune responses and tumor surveillance.