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Human HLA-A*0201 NY-ESO-1 complex Recombinant Protein (C-10His) (RPES6383)

SKU:
RPES6383
Product Type:
Recombinant Protein
Species:
Human
€199

Description

Product Name:Human HLA-A*0201 NY-ESO-1 complex Recombinant Protein (C-10His)
Product Code:RPES6383
Size:10µg
Species:Human
Expression Host:HEK293 Cells
Synonyms:MHC, MY-ESO-1, HLA-A*0201 NY-ESO-1 complex Protein
Mol Mass:49.1 kDa
AP Mol Mass:55-60 kDa
Tag:C-10His
Purity:> 90 % as determined by reducing SDS-PAGE.
Endotoxin Level:< 1.0 EU per μg of the protein as determined by the LAL method.
Bio Activity:Testing in progress
Sequence:SLLMWITQC&Ile21-Met119&Gly25-Ile308(Ala269Val)
Accession:P61769&P01892
Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Shipping:This product is provided as lyophilized powder which is shipped with ice packs.
Formulation:Lyophilized from a 0.2 μm filtered solution of 20mM PB, 500mM NaCl, pH7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manu
Reconstitution:Please refer to the printed manual for detailed information.
Background:NY-ESO-1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses, together with its restricted expression pattern, have rendered it a good candidate target for cancer immunotherapy. Optimally assembled peptide-HLA-B2M trimer translocates to the surface of antigen-presenting cells, where it interacts with TCR and CD8 coreceptor on the surface of T cells.

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