Human HEBP1 Recombinant Protein (RPPB3668)
- SKU:
- RPPB3668
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q9NRV9
Description
| Product Name: | Human HEBP1 Recombinant Protein |
| Product Code: | RPPB3668 |
| Size: | 10µg |
| Species: | Human |
| Target: | HEBP1 |
| Synonyms: | Heme-binding protein 1, p22HBP, HEBP1, HBP, HEBP. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | HEBP1 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 30% glycerol and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMLGMIKN SLFGSVETWP WQVLSKGDKE EVAYEERACE GGKFATVEVT DKPVDEALRE AMPKVAKYAG GTNDKGIGMG MTVPISFAVF PNEDGSLQKK LKVWFRIPNQ FQSDPPAPSD KSVKIEEREG ITVYSMQFGG YAKEADYVAQ ATRLRAALEG TATYRGDIYF CTGYDPPMKP YGRRNEIWLL KT |
Heme Binding Protein 1 (HEBP1) is an intracellular tetrapyrrole-binding protein. HEBP1 is comprised of a natural chemoattractant peptide of 21 amino acids at the N-terminus, which is a natural ligand for formyl peptide receptor-like receptor 2 (FPRL2) and stimulates calcium mobilization and chemotaxis in monocytes and dendritic cells.
HEBP1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 212 amino acids (1-189 a.a.) and having a molecular mass of 23.5kDa.HEBP1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | HEBP1: May bind free porphyrinogens that may be present in the cell and thus facilitate removal of these potentially toxic compound. Binds with a high affinity to one molecule of heme or porphyrins. It binds metalloporphyrins, free porphyrins and N- methylprotoporphyrin with similar affinities. Belongs to the HEBP family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 12p13.1 Cellular Component: extracellular region Molecular Function:heme binding Biological Process: circadian rhythm |
| NCBI Summary: | The full-length protein encoded by this gene is an intracellular tetrapyrrole-binding protein. This protein includes a natural chemoattractant peptide of 21 amino acids at the N-terminus, which is a natural ligand for formyl peptide receptor-like receptor 2 (FPRL2) and promotes calcium mobilization and chemotaxis in monocytes and dendritic cells. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9NRV9 |
| NCBI GenInfo Identifier: | 74734327 |
| NCBI Gene ID: | 50865 |
| NCBI Accession: | Q9NRV9.1 |
| UniProt Secondary Accession: | Q9NRV9,Q9Y5Z5, A8K1G2, |
| UniProt Related Accession: | Q9NRV9 |
| Molecular Weight: | 21,097 Da |
| NCBI Full Name: | Heme-binding protein 1 |
| NCBI Synonym Full Names: | heme binding protein 1 |
| NCBI Official Symbol: | HEBP1�� |
| NCBI Official Synonym Symbols: | HBP; HEBP�� |
| NCBI Protein Information: | heme-binding protein 1 |
| UniProt Protein Name: | Heme-binding protein 1 |
| UniProt Synonym Protein Names: | p22HBP |
| Protein Family: | Heme-binding protein |
| UniProt Gene Name: | HEBP1�� |
| UniProt Entry Name: | HEBP1_HUMAN |
