Human GRM5 full length protein-synthetic nanodisc (HDFP316)
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- SKU:
- HDFP316
- Size:
- 10μg
- Target:
- GRM5
- Tag:
- C-Flag Tag
- Expression Host:
- HEK293
- Conjugate:
- Unconjugated
Description
| Product Name: | Nanodisc Human GRM5 Protein |
| SKU: | HDFP316 |
| Size: | 10μg |
| Target: | GRM5 |
| Tag: | C-Flag Tag |
| Expression Host: | HEK293 |
| Conjugate: | Unconjugated |
| Synonyms: | GPRC1E, MGLUR5, PPP1R86, mGlu5 |
| Protein Families: | GPCR, Transmembrane, Druggable Genome. |
| Protein Description: | Human GRM5 full length protein-synthetic nanodisc |
| Protein Pathways: | GPCRDB Class C Metabotropic glutamate pheromone. |
| Molecular Weight: | The human full length GRM5 protein has a MW of 132.5kDa |
This gene encodes a member of the G-protein coupled receptor 3 protein family. The encoded protein is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. This protein may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]
| Uniprot ID: | P41594 |
| Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Usage: | Research use only |
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