Nanodisc Human GRIK2-Strep Protein (HDFP1467)
- SKU:
- HDFP1467
- Size:
- 10μg
- Target:
- GRIK2
- Tag:
- C-Flag&Strep Tag
- Expression Host:
- HEK293
- Conjugate:
- Unconjugated
Description
| Product Name: | Nanodisc Human GRIK2-Strep Protein |
| SKU: | HDFP1467 |
| Size: | 10μg |
| Target: | GRIK2 |
| Tag: | C-Flag&Strep Tag |
| Expression Host: | HEK293 |
| Conjugate: | Unconjugated |
| Synonyms: | EAA4, GLR6, GLUK6, GLUR6, GluK2, MRT6 |
| Protein Families: | Ion Channels: Glutamate Receptors. |
| Protein Description: | Human GRIK2-Strep full length protein-synthetic nanodisc |
| Molecular Weight: | The human full length GRIK2-Strep protein has a MW of 102.6 kDa |
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. The subunit encoded by this gene is subject to RNA editing at multiple sites within the first and second transmembrane domains, which is thought to alter the structure and function of the receptor complex. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene. Mutations in this gene have been associated with autosomal recessive cognitive disability. [provided by RefSeq, Jul 2008]
| Uniprot ID: | Q13002 |
| Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Usage: | Research use only |
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