Human GOLM1 Recombinant Protein (RPPB3627)
- SKU:
- RPPB3627
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q8NBJ4
Description
| Product Name: | Human GOLM1 Recombinant Protein |
| Product Code: | RPPB3627 |
| Size: | 10µg |
| Species: | Human |
| Target: | GOLM1 |
| Synonyms: | Golgi Membrane Protein 1, Chromosome 9 Open Reading Frame 155, Epididymis Luminal Protein 46, Golgi Membrane Protein GP73, Golgi Phosphoprotein 2, GOLPH2, Golgi Protein 73-KD, PSEC0257, bA379P1.3, HEL46, C9orf155, GP73. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | GOLM1 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 0.1M NaCl, 1mM DTT and 20% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles. |
| Purity: | Greaterthan 85.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSSSRSVDL QTRIMELEGR VRRAAAERGA VELKKNEFQG ELEKQREQLD KIQSSHNFQL ESVNKLYQDE KAVLVNNITT GERLIRVLQD QLKTLQRNYG RLQQDVLQFQ KNQTNLERKF SYDLSQCINQ MKEVKEQCEE RIEEVTKKGN EAVASRDLSE NNDQRQQLQA LSEPQPRLQA AGLPHTEVPQ GKGNVLGNSK SQTPAPSSEV VLDSKRQVEK EETNEIQVVN EEPQRDRLPQ EPGREQVVED RPVGGRGFGG AGELGQTPQV QAALSVSQEN PEMEGPERDQ LVIPDGQEEE QEAAGEGRNQ QKLRGEDDYN MDENEAESET DKQAALAGND RNIDVFNVED QKRDTINLLD QREKRNHTL |
GOLM1 is a type II Golgi transmembrane protein. GOLM1 processes protein synthesized in the rough endoplasmic reticulum and aids in transporting protein cargo through the Golgi apparatus. The expression of this encoded protein was shown to be upregulated in response to viral infection. Additionally, since GOLM1 is highly regulated in cells, it can be used as a molecular biomarker for cancer.
GOLM1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 389 amino acids (36-401 a.a) and having a molecular mass of 44.0kDa.GOLM1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | GOLM1: Unknown. Cellular response protein to viral infection. Belongs to the GOLM1/CASC4 family. 2 isoforms of the human protein are produced by alternative initiation. |
| UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 9q21.33 Cellular Component: Golgi apparatus; extracellular space; integral to plasma membrane Molecular Function:protein binding Biological Process: regulation of lipid metabolic process; nuclear organization and biogenesis |
| UniProt Code: | Q8NBJ4 |
| NCBI GenInfo Identifier: | 51316027 |
| NCBI Gene ID: | |
| NCBI Accession: | Q8NBJ4.1 |
| Molecular Weight: | 45kDa |
| NCBI Full Name: | Golgi membrane protein 1 |
| UniProt Protein Name: | Golgi membrane protein 1 |
| UniProt Synonym Protein Names: | Golgi membrane protein GP73; Golgi phosphoprotein 2 |
| Protein Family: | Golgi membrane protein |
| UniProt Gene Name: | GOLM1�� |
| UniProt Entry Name: | GOLM1_HUMAN |
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