Human GNPNAT1 Recombinant Protein (RPPB1720)
- SKU:
- RPPB1720
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q96EK6
- Research Area:
- Enzymes
Description
| Product Name: | Human GNPNAT1 Recombinant Protein |
| Product Code: | RPPB1720 |
| Size: | 10µg |
| Species: | Human |
| Target: | GNPNAT1 |
| Synonyms: | Gpnat1, GNPNAT, GNA1, EC 2.3.1.4, FLJ10607, Glucosamine-Phosphate N-Acetyltransferase 1, Phosphoglucosamine acetylase, Phosphoglucosamine transacetylase, Glucosamine 6-Phosphate N-Acetyltransferase. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | The GNPNAT1 protein solution (0.5mg/1ml) is formulated in 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 0.1M NaCl and 30% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks.�Store, frozen at -20°C for longer periods of time.Please avoid freeze thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMKPDETP MFDPSLLKEV DWSQNTATFS PAISPTHPGE GLVLRPLCTA DLNRGFFKVL GQLTETGVVS PEQFMKSFEH MKKSGDYYVT VVEDVTLGQI VATATLIIEH KFIHSCAKRG RVEDVVVSDE CRGKQLGKLL LSTLTLLSKK LNCYKITLEC LPQNVGFYKK FGYTVSEENY MCRRFLK |
GNPNAT1 is a member of the GNA1 subfamily of the larger acetyltransferase family of proteins. GNPNAT1 is limited to the Golgi apparatus and the endosome. GNPNAT1 is vital for UDPGlcNAc biosynthesis pathway. GNPNAT1 catalyzes the synthesis of GlcNAc6P from AcCoA and GlcN6P, a step in the UDP-GlcNAc6P formation pathway.
GNPNAT1 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 207 amino acids (1-184a.a.) and having a molecular mass of 23.1KDa.GNPNAT1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | GNPNAT1: Belongs to the acetyltransferase family. GNA1 subfamily. |
| UniProt Protein Details: | Protein type:Acetyltransferase; EC 2.3.1.4; Carbohydrate Metabolism - amino sugar and nucleotide sugar Chromosomal Location of Human Ortholog: 14q22.1 Cellular Component: Golgi membrane; late endosome; ER-Golgi intermediate compartment; endosome membrane; cytosol Molecular Function:monosaccharide binding; glucosamine 6-phosphate N-acetyltransferase activity Biological Process: cellular protein metabolic process; dolichol-linked oligosaccharide biosynthetic process; N-acetylglucosamine metabolic process; UDP-N-acetylglucosamine biosynthetic process; protein amino acid N-linked glycosylation via asparagine; liver development; post-translational protein modification; glucosamine metabolic process |
| UniProt Code: | Q96EK6 |
| NCBI GenInfo Identifier: | 47116568 |
| NCBI Gene ID: | 64841 |
| NCBI Accession: | Q96EK6.1 |
| UniProt Related Accession: | Q96EK6 |
| Molecular Weight: | 20,749 Da |
| NCBI Full Name: | Glucosamine 6-phosphate N-acetyltransferase |
| NCBI Synonym Full Names: | glucosamine-phosphate N-acetyltransferase 1 |
| NCBI Official Symbol: | GNPNAT1�� |
| NCBI Official Synonym Symbols: | GNPNAT; Gpnat1�� |
| NCBI Protein Information: | glucosamine 6-phosphate N-acetyltransferase; phosphoglucosamine acetylase; phosphoglucosamine transacetylase |
| UniProt Protein Name: | Glucosamine 6-phosphate N-acetyltransferase |
| UniProt Synonym Protein Names: | Phosphoglucosamine acetylase; Phosphoglucosamine transacetylase |
| UniProt Gene Name: | GNPNAT1�� |
| UniProt Entry Name: | GNA1_HUMAN |
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