Human GLTP Recombinant Protein (RPPB3607)
- SKU:
- RPPB3607
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q9NZD2
Description
| Product Name: | Human GLTP Recombinant Protein |
| Product Code: | RPPB3607 |
| Size: | 10µg |
| Species: | Human |
| Target: | GLTP |
| Synonyms: | Glycolipid transfer protein, GLTP. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | GLTP protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.2M NaCl, 20% glycerol and 1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 85.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMALLAEH LLKPLPADKQ IETGPFLEAV SHLPPFFDCL GSPVFTPIKA DISGNITKIK AVYDTNPAKF RTLQNILEVE KEMYGAEWPK VGATLALMWL KRGLRFIQVF LQSICDGERD ENHPNLIRVN ATKAYEMALK KYHGWIVQKI FQAALYAAPY KSDFLKALSK GQNVTEEECL EKIRLFLVNY TATIDVIYEM YTQMNAELNY KV |
Glycolipid transfer protein (GLTP) accelerates the intermembrane transfer of different glycolipids. GLTP catalyzes the transfer of various glycosphingolipids between membranes however does not catalyze the transfer of phospholipids. GLTP is involved in the intracellular translocation of glucosylceramides. The GLTP protein is similar to bovine and porcine proteins which accelerate transfer of certain glycosphingolipids and glyceroglycolipids between membranes. GLTP is assumed to be a cytoplasmic protein. GLTP is detected in fibroblasts and in various cancer cell lines.
GLTP Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 232 amino acids (1-209 a.a.) and having a molecular mass of 26.2kDa.GLTP is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | GLTP: Accelerates the intermembrane transfer of various glycolipids. Catalyzes the transfer of various glycosphingolipids between membranes but does not catalyze the transfer of phospholipids. May be involved in the intracellular translocation of glucosylceramides. Belongs to the GLTP family. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 12q24.11 Cellular Component: membrane; cytoplasm Molecular Function:glycolipid transporter activity; lipid binding; glycolipid binding Biological Process: glycolipid transport |
| NCBI Summary: | The protein encoded by this gene is similar to bovine and porcine proteins which accelerate transfer of certain glycosphingolipids and glyceroglycolipids between membranes. It is thought to be a cytoplasmic protein. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9NZD2 |
| NCBI GenInfo Identifier: | 20138399 |
| NCBI Gene ID: | 51228 |
| NCBI Accession: | Q9NZD2.3 |
| UniProt Related Accession: | Q9NZD2 |
| Molecular Weight: | Observed: 24 kDaPredicted: 24 kDa |
| NCBI Full Name: | Glycolipid transfer protein |
| NCBI Synonym Full Names: | glycolipid transfer protein |
| NCBI Official Symbol: | GLTP�� |
| NCBI Protein Information: | glycolipid transfer protein |
| UniProt Protein Name: | Glycolipid transfer protein |
| Protein Family: | Glycolipid transfer protein |
| UniProt Gene Name: | GLTP�� |
| UniProt Entry Name: | GLTP_HUMAN |
Related Products
Human Recombinant Protein S100P Recombinant Protein (His Tag) (RPES6517)
Human Recombinant Protein S100P Recombinant Protein (His Tag) (RPES5309)
