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Human GALR1-Strep full length protein-synthetic nanodisc (HDFP980)

SKU:
HDFP980
Size:
10μg
Target:
GALR1
Tag:
C-Flag&Strep Tag
Expression Host:
HEK293
Conjugate:
Unconjugated
€1,249

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:Nanodisc Human GALR1-Strep Protein
SKU:HDFP980
Size:10μg
Target:GALR1
Tag:C-Flag&Strep Tag
Expression Host:HEK293
Conjugate:Unconjugated
Synonyms:GALNR, GALNR1
Protein Families:Transmembrane, Druggable Genome.
Protein Description:Human GALR1-Strep full length protein-synthetic nanodisc
Protein Pathways:GPCRDB Class A Rhodopsin-like, Peptide GPCRs, Metabolic and Obesity.
Molecular Weight:The human full length GALR1-Strep protein has a MW of 39 kDa

The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart. [provided by RefSeq, Jul 2008]

Uniprot ID:P47211
Formulation & Reconstitution:Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping:Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Usage:Research use only

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