Human GAGE2D Recombinant Protein (RPPB3576)
- SKU:
- RPPB3576
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q9UEU5
Description
| Product Name: | Human GAGE2D Recombinant Protein |
| Product Code: | RPPB3576 |
| Size: | 10µg |
| Species: | Human |
| Target: | GAGE2D |
| Synonyms: | G Antigen 2D, Cancer/Testis Antigen 4.8, CT4.8, GAGE-8, GAGE8,G Antigen 8. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | GAGE2D protein solution (1mg/ml) containing 20mM Tris-HClbuffer (pH8.0), 10% glycerol and 0.1M NaCl. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMSWRGRS TYRPRPRRYV EPPEMIGPMR PEQFSDEVEP ATPEEGEPATQRQDPAAAQE GEDEGASAGQ GPKPEADSQE QGHPQTGCEC EDGPDGQEMD PPNPEEVKTP EEGEKQSQC |
| UniProt Code: | Q9UEU5 |
GAGE2D is a member of the GAGE family, which organized in clusteredrepeats. In addition, they have a high degree of predicted sequence identity, butdiffer by scattered single nucleotide substitution. The first GAGE nomenclature was based onidentified mRNA sequences; however the high identity of the GAGE members made it impossible toseparate products of paralogous genes from polymorph products. Moreover GAGE2Dis not expressed in normal tissues, except in testis; however it is expressedby a large proportion of tumors of various histological origins.
GAGE2D Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 139 amino acids (1-116 a.a) and having a molecular mass of 15.2kDa (Molecular size on SDS-PAGE will appear higher).GAGE2D is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
