Human FZD1 full length protein-synthetic nanodisc (HDFP233)
- SKU:
- HDFP233
- Size:
- 10μg
- Target:
- FZD1
- Tag:
- C-Flag Tag
- Expression Host:
- HEK293
- Conjugate:
- Unconjugated
Description
| Product Name: | Nanodisc Human FZD1 Protein |
| SKU: | HDFP233 |
| Size: | 10μg |
| Target: | FZD1 |
| Tag: | C-Flag Tag |
| Expression Host: | HEK293 |
| Conjugate: | Unconjugated |
| Synonyms: | Frizzled-1; Fz-1; hFz1; FzE1 |
| Protein Families: | GPCR, Transmembrane, Druggable Genome. |
| Protein Description: | Human FZD1 full length protein-synthetic nanodisc |
| Protein Pathways: | Adipogenesis, Wnt NetPath 8, Wnt signaling, Wnt signaling and pluripotency, Cancer, Notch, Wnt Pathway, Stem Cell. |
| Molecular Weight: | The human full length FZD1 protein has a MW of 71.2kDa |
Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD1 protein contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. The FZD1 transcript is expressed in various tissues. [provided by RefSeq, Jul 2008]
| Uniprot ID: | Q9UP38 |
| Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Usage: | Research use only |
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