Human FGF 22 Recombinant Protein (RPPB0248)
- SKU:
- RPPB0248
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q9HCT0
- Research Area:
- Growth Factors & Cytokines
Description
| Product Name: | Human FGF 22 Recombinant Protein |
| Product Code: | RPPB0248 |
| Size: | 10µg |
| Species: | Human |
| Target: | FGF 22 |
| Synonyms: | Fibroblast growth factor 22, FGF-22. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered white lyophilized powder. |
| Formulation: | The sterile protein powder is lyophilized with no additives. |
| Solubility: | It is recommended to reconstitute the lyophilized Fibroblast Growth Factor-22 sterile 18M?-cm H2O not less than 100�g/ml, which can then be further diluted to other aqueous solutions. |
| Stability: | Lyophilized Fibroblast Growth Factor 22 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution FGF-22 should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles. |
| Purity: | Greater than 97.0% as determined by(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE. |
| Amino Acid Sequence: | MTPSASRGPR SYPHLEGDVR WRRLFSSTHF FLRVDPGGRV QGTRWRHGQD SILEIRSVHV GVVVIKAVSS GFYVAMNRRG RLYGSRLYTV DCRFRERIEE NGHNTYASQR WRRRGQPMFL ALDRRGGPRP GGRTRRYHLS AHFLPVLVS |
FGF22 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development.
Fibroblast Growth Factor-22 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 149 amino acids and having a molecular mass of 17.3 kDa. The FGF-22 is purified by chromatographic techniques.
| UniProt Protein Function: | FGF22: Plays a role in the fasting response, glucose homeostasis, lipolysis and lipogenesis. Can stimulate cell proliferation (in vitro). May be involved in hair development. Belongs to the heparin-binding growth factors family. |
| UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 19p13.3 Cellular Component: Golgi apparatus; extracellular space; cell surface; extracellular region; nucleolus Molecular Function:growth factor activity; fibroblast growth factor receptor binding Biological Process: epidermal growth factor receptor signaling pathway; phosphoinositide-mediated signaling; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; insulin receptor signaling pathway; innate immune response; cell differentiation |
| NCBI Summary: | The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] |
| UniProt Code: | Q9HCT0 |
| NCBI GenInfo Identifier: | 13626689 |
| NCBI Gene ID: | 27006 |
| NCBI Accession: | Q9HCT0.1 |
| UniProt Secondary Accession: | Q9HCT0,B2RPH4, |
| UniProt Related Accession: | Q9HCT0 |
| Molecular Weight: | 19,663 Da |
| NCBI Full Name: | Fibroblast growth factor 22 |
| NCBI Synonym Full Names: | fibroblast growth factor 22 |
| NCBI Official Symbol: | FGF22�� |
| NCBI Protein Information: | fibroblast growth factor 22; FGF-22 |
| UniProt Protein Name: | Fibroblast growth factor 22 |
| Protein Family: | Fibroblast growth factor |
| UniProt Gene Name: | FGF22�� |
| UniProt Entry Name: | FGF22_HUMAN |
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