Human FANK1 Recombinant Protein (RPPB3517)
- SKU:
- RPPB3517
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q8TC84
Frequently bought together:
Description
| Product Name: | Human FANK1 Recombinant Protein |
| Product Code: | RPPB3517 |
| Size: | 20µg |
| Species: | Human |
| Target: | FANK1 |
| Synonyms: | Fibronectin Type 3 And Ankyrin Repeat Domains 1, 1700007B22Rik. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | FANK1 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 0.15M NaCl, 1mM DTT, 0.1mM PMSF and 20% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles. |
| Purity: | Greaterthan 90.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMEPQKIM PPSKPHPPVV GKVTHHSIEL YWDLEKKAKR QGPQEQWFRF SIEEEDPKMH TYGIIYTGYA TKHVVEGLEP RTLYRFRLKV TSPSGECEYS PLVSVSTTRE PISSEHLHRA VSVNDEDLLV RILQGGRVKV DVPNKFGFTA LMVAAQKGYT RLVKILVSNG TDVNLKNGSG KDSLMLACYA GHLDVVKYLR RHGASWQARD LGGCTALHWA ADGGHCSVIE WMIKDGCEVD VVDTGSGWTP LMRVSAVSGN QRVASLLIDA GANVNVKDRN GKTPLMVAVL NNHEELVQLL LDKGADASVK NEFGKGVLEM ARVFDRQSVV SLLEERKKKQ RPKKSCVC |
FANK1 was localized in the nuclei of identical cells in the seminiferous epithelium. Depending on its nuclear localization, a gene ontology analysis proposes that FANK1 has a DNA binding activity therefor operates as a transcription factor. The extremely controlled expression of FANK1, suggests that it takes part in regulating gene expression in the transition from the meiotic phase to the haploid phase throughout spermatogenesis.
FANK1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 368 amino acids (1-345 a.a) and having a molecular mass of 40.7kDa.FANK1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | FANK1: 3 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 10q26.2Cellular Component: cytoplasm; nucleoplasm |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8TC84 |
| NCBI GenInfo Identifier: | 148596917 |
| NCBI Gene ID: | 92565 |
| NCBI Accession: | NP_660278.3 |
| UniProt Secondary Accession: | Q8TC84,Q6UXY9, Q6X7T6 |
| UniProt Related Accession: | Q8TC84 |
| Molecular Weight: | 41,072 Da |
| NCBI Full Name: | fibronectin type 3 and ankyrin repeat domains protein 1 |
| NCBI Synonym Full Names: | fibronectin type III and ankyrin repeat domains 1 |
| NCBI Official Symbol: | FANK1�� |
| NCBI Official Synonym Symbols: | HSD13�� |
| NCBI Protein Information: | fibronectin type 3 and ankyrin repeat domains protein 1 |
| UniProt Protein Name: | Fibronectin type 3 and ankyrin repeat domains protein 1 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Fibronectin type 3 and ankyrin repeat domains protein |
| UniProt Gene Name: | FANK1�� |
| UniProt Entry Name: | FANK1_HUMAN |
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