Human FABP7 Recombinant Protein (RPPB3503)
- SKU:
- RPPB3503
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- O15540
Description
| Product Name: | Human FABP7 Recombinant Protein |
| Product Code: | RPPB3503 |
| Size: | 25µg |
| Species: | Human |
| Target: | FABP7 |
| Synonyms: | MRG, BLBP, FABPB, B-FABP, DKFZp547J2313, Fatty acid-binding protein brain, Fatty acid-binding protein 7, Brain lipid-binding protein, Mammary-derived growth inhibitor related, FABP7. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered colorless solution. |
| Formulation: | The FABP7 protein solution contains 25mM Tris-HCl pH7.5, 2mM EDTA and 10% Glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks.Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 95.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MVEAFCATWK LTNSQNFDEY MKALGVGFAT RQVGNVTKPT VIISQEGDKV VIRTLSTFKN TEISFQLGEE FDETTADDRN CKSVVSLDGD KLVHIQKWDG KETNFVREIK DGKMVMTLTF GDVVAVRHYE KA |
FABP7 is a brain fatty acid binding protein. Fatty acid binding proteins (FABPs) are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs are are inovlved in fatty acid uptake, transport, and metabolism. FABP7 is expressed in radial glia by the activation of Notch receptors and binds DHA with the highest affinity among all of FABPs. FABP7 plays an important role in transport of hydrophobic ligand with potential morphogenic activity during cns development. FABP7 is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers (by similarity).
FABP7 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 132 amino acids and having a molecular mass of 14 kDa.
| UniProt Protein Function: | FABP7: B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. It is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. |
| UniProt Protein Details: | Protein type:Cell development/differentiation; Lipid-binding; Cell cycle regulation Chromosomal Location of Human Ortholog: 6q22-q23 Cellular Component: cell projection; cell soma; cytoplasm; nucleus Molecular Function:transporter activity; lipid binding Biological Process: negative regulation of cell proliferation; nervous system development; epithelial cell proliferation; prepulse inhibition; neurogenesis; transport; cell proliferation in forebrain |
| NCBI Summary: | The protein encoded by this gene is a brain fatty acid binding protein. Fatty acid binding proteins (FABPs) are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs are thought to play roles in fatty acid uptake, transport, and metabolism. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O15540 |
| NCBI GenInfo Identifier: | 3122076 |
| NCBI Gene ID: | 2173 |
| NCBI Accession: | O15540.3 |
| UniProt Secondary Accession: | O15540,O14951, Q6IAU7, Q9H047, B2R4L1, |
| UniProt Related Accession: | O15540 |
| Molecular Weight: | 132 |
| NCBI Full Name: | Fatty acid-binding protein, brain |
| NCBI Synonym Full Names: | fatty acid binding protein 7, brain |
| NCBI Official Symbol: | FABP7�� |
| NCBI Official Synonym Symbols: | MRG; BLBP; FABPB; B-FABP; LTR2-FABP7�� |
| NCBI Protein Information: | fatty acid-binding protein, brain; brain lipid binding protein; brain lipid-binding protein; fatty acid-binding protein 7; Hypothetical protein DKFZp547J2313; brain-type fatty acid-binding protein; mammary-derived growth inhibitor related; mammary-derived |
| UniProt Protein Name: | Fatty acid-binding protein, brain |
| UniProt Synonym Protein Names: | Brain lipid-binding protein; BLBP; Brain-type fatty acid-binding protein; B-FABP; Fatty acid-binding protein 7; Mammary-derived growth inhibitor related |
| UniProt Gene Name: | FABP7�� |
| UniProt Entry Name: | FABP7_HUMAN |
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