Nanodisc Human F2RL1-Strep Protein (HDFP779)
- SKU:
- HDFP779
- Size:
- 10μg
- Target:
- F2RL1
- Tag:
- C-Flag&Strep Tag
- Expression Host:
- HEK293
- Conjugate:
- Unconjugated
Frequently bought together:
Description
| Product Name: | Nanodisc Human F2RL1-Strep Protein |
| SKU: | HDFP779 |
| Size: | 10μg |
| Target: | F2RL1 |
| Tag: | C-Flag&Strep Tag |
| Expression Host: | HEK293 |
| Conjugate: | Unconjugated |
| Synonyms: | GPR11; PAR2 |
| Protein Families: | Druggable Genome, GPCR, Transmembrane. |
| Protein Description: | Human F2RL1-Strep full length protein-synthetic nanodisc |
| Protein Pathways: | Neuroactive ligand-receptor interaction. |
| Molecular Weight: | The human full length F2RL1-Strep protein has a MW of 44.1 kDa |
A member of the G-protein coupled receptor 1 family of proteins. The encoded cell surface receptor is activated through proteolytic cleavage of its extracellular amino terminus, resulting in a new amino terminus that acts as a tethered ligand that binds to an extracellular loop domain. Activation of the receptor has been shown to stimulate vascular smooth muscle relaxation, dilate blood vessels, increase blood flow, and lower blood pressure. This protein is also important in the inflammatory response, as well as innate and adaptive immunity.
| Uniprot ID: | P55085 |
| Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Usage: | Research use only |
Related Products
