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Human ERGIC3 Recombinant Protein (RPPB3460)

SKU:
RPPB3460
Product Type:
Recombinant Protein
Species:
Human
Uniprot:
Q9Y282
€469

Description

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Product Name:Human ERGIC3 Recombinant Protein
Product Code:RPPB3460
Size:20µg
Species:Human
Target:ERGIC3
Synonyms:ERGIC And Golgi 3,Serologically Defined Breast Cancer Antigen NY-BR-84, Serologically Defined Breast Cancer Antigen 84, C20orf47, SDBCAG84, Erv46, Endoplasmic Reticulum-Golgi Intermediate Compartment Protein 3, Endoplasmic Reticulum-Localized Protein ERp43,Chromosome 20 Open Reading Frame 47,DJ477O4.2, NY-BR-84, PRO0989,CGI-54, ERGIC3.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered clear solution.
Formulation:ERGIC3 protein solution (1mg/ml) containing Phosphate buffered saline (pH7.4), 10% glycerol and 1mM DTT.
Stability:Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Purity:Greater than 95.0% as determined by SDS-PAGE.
Amino Acid Sequence:�MGSSHHHHHH SSGLVPRGSH MGSQYYLTTE VHPELYVDKS RGDKLKINID VLFPHMPCAY LSIDAMDVAG EQQLDVEHNL FKQRLDKDGI PVSSEAERHE LGKVEVTVFD PDSLDPDRCE SCYGAEAEDI KCCNTCEDVR EAYRRRGWAF KNPDTIEQCR REGFSQKMQE QKNEGCQVYG FLEVNKVAGN FHFAPGKSFQ QSHVHVHDLQ SFGLDNINMT HYIQHLSFGE DYPGIVNPLD HTNVTAPQAS MMFQYFVKVV PTVYMKVDGE VLRTNQFSVT RHEKVANGLL GDQGLPGVFV LYELSPMMVK LTEKHRSF

ERGIC And Golgi 3, also known as ERGIC3 is a member of the ERGIC familyand interacts with ERGIC1/ERGIC32. ERGIC3 takes part in the transport betweenendoplasmic reticulum and Golgi. One of the diseases which is associated with ERGIC3is Breast Cancer.

ERGIC3 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 318 amino acids (47-341 a.a) and having a molecular mass of 36.1kDa.ERGIC3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

UniProt Protein Function:SDBCAG84: Possible role in transport between endoplasmic reticulum and Golgi. Belongs to the ERGIC family. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Membrane protein, multi-pass; Motility/polarity/chemotaxis; Vesicle; Membrane protein, integral

Chromosomal Location of Human Ortholog: 20pter-q12

Cellular Component: endoplasmic reticulum membrane; ER-Golgi intermediate compartment membrane; Golgi apparatus; integral to membrane; membrane

Biological Process: vesicle-mediated transport

UniProt Code:Q9Y282
NCBI GenInfo Identifier:37999823
NCBI Gene ID:51614
NCBI Accession:Q9Y282.1
UniProt Secondary Accession:Q9Y282,Q5JWS3, Q6ZWP7, Q9H276, Q9P1L3,
UniProt Related Accession:Q9Y282
Molecular Weight:43,772 Da
NCBI Full Name:Endoplasmic reticulum-Golgi intermediate compartment protein 3
NCBI Synonym Full Names:ERGIC and golgi 3
NCBI Official Symbol:ERGIC3��
NCBI Official Synonym Symbols:Erv46; CGI-54; PRO0989; C20orf47; NY-BR-84; SDBCAG84; dJ477O4.2��
NCBI Protein Information:endoplasmic reticulum-Golgi intermediate compartment protein 3
UniProt Protein Name:Endoplasmic reticulum-Golgi intermediate compartment protein 3
UniProt Synonym Protein Names:Serologically defined breast cancer antigen NY-BR-84
Protein Family:Endoplasmic reticulum-Golgi intermediate compartment protein
UniProt Gene Name:ERGIC3��
UniProt Entry Name:ERGI3_HUMAN

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