Human ELP5 Recombinant Protein (RPPB3443)
- SKU:
- RPPB3443
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q8TE02
Description
| Product Name: | Human ELP5 Recombinant Protein |
| Product Code: | RPPB3443 |
| Size: | 10µg |
| Species: | Human |
| Target: | ELP5 |
| Synonyms: | C17orf81, DERP6, HSPC002, MST071, MSTP071, Dermal papilla-derived protein 6, S-phase 2 protein, ELP5. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | ELP5 protein solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 20% glycerol and�1mM DTT. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 80.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMTPSEGA RAGTGRELEM LDSLLALGGL VLLRDSVEWE GRSLLKALVK KSALCGEQVH ILGCEVSEEE FREGFDSDIN NRLVYHDFFR DPLNWSKTEE AFPGGPLGAL RAMCKRTDPV PVTIALDSLS WLLLRLPCTT LCQVLHAVSH QDSCPGDSSS VGKVSVLGLL HEELHGPGPV GALSSLAQTE VTLGGTMGQA SAHILCRRPR QRPTDQTQWF SILPDFSLDL QEGPSVESQP YSDPHIPPVD PTTHLTFNLH LSKKEREARD SLILPFQFSS EKQQALLRPR PGQATSHIFY EPDAYDDLDQ EDPDDDLDI |
Elongator acetyltransferase complex subunit 5 (ELP5) is a member of the ELP5 family. ELP5 functions as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is participated in transcriptional elongation. Elongator plays a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. ELP5 takes part� in cell migration and is widely expressed in in heart, brain, liver, skeletal muscle and testis.
ELP5 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 339 amino acids (1-316 a.a.) and having a molecular mass of 37.2kDa.ELP5 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. Involved in cell migration. May be involved in TP53-mediated transcriptional regulation. |
| UniProt Code: | Q8TE02 |
| NCBI GenInfo Identifier: | 44662830 |
| NCBI Gene ID: | 23587 |
| NCBI Accession: | NP_056177.3 |
| UniProt Secondary Accession: | Q8TE02,Q659B6, Q7Z2T4, Q8TDR9, Q9BUB2, Q9Y2Q4, A8K1M5 D3DTN9, |
| UniProt Related Accession: | Q8TE02 |
| Molecular Weight: | Calculated: 19kDa; 30kDa; 34kDa; 35kDaObserved: 38kDa |
| NCBI Full Name: | elongator complex protein 5 isoform 1 |
| NCBI Synonym Full Names: | elongator acetyltransferase complex subunit 5 |
| NCBI Official Symbol: | ELP5�� |
| NCBI Official Synonym Symbols: | DERP6; MST071; HSPC002; MSTP071; C17orf81�� |
| NCBI Protein Information: | elongator complex protein 5 |
| UniProt Protein Name: | Elongator complex protein 5 |
| UniProt Synonym Protein Names: | Dermal papilla-derived protein 6; S-phase 2 protein |
| Protein Family: | Elongator complex protein |
| UniProt Gene Name: | ELP5�� |
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