Human DUSP23 Recombinant Protein (RPPB1599)
- SKU:
- RPPB1599
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q9BVJ7
- Research Area:
- Enzymes
Frequently bought together:
Description
| Product Name: | Human DUSP23 Recombinant Protein |
| Product Code: | RPPB1599 |
| Size: | 10µg |
| Species: | Human |
| Target: | DUSP23 |
| Synonyms: | Dual specificity protein phosphatase 23, Low molecular mass dual specificity phosphatase 3, LDP-3, VH1-like phosphatase Z, DUSP23, LDP3, VHZ, VH1-Like Member Z, EC 3.1.3.16, EC 3.1.3.48, DUSP25, MOSP, LDP3, Dual Specificity Phosphatase 23, VH1-Like Phosphatase Z, LDP-3, VHZ, Low-Molecular-Mass Dual-Specificity Phosphatase 3, Low Molecular Mass Dual Specificity Phosphatase 3, Dual Specificity Protein, Phosphatase 23, Testicular Tissue Protein Li 59. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | DUSP23 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 2mM DTT, 10% glycerol and 100mM NaCl. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 90% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGVQPPNFSW VLPGRLAGLA LPRLPAHYQF LLDLGVRHLV SLTERGPPHS DSCPGLTLHR LRIPDFCPPA PDQIDRFVQI VDEANARGEA VGVHCALGFG RTGTMLACYL VKERGLAAGD AIAEIRRLRP GSIETYEQEK AVFQFYQRTK |
| Biological Activity: | Specific activity is > 200 units/mg, and is defined as the amount of enzyme that hydrolyzes 1.0 nmole of p-nitrophenyl phosphate (pNPP) per minute at pH 7.5 at 37�C. |
DUSP23 is a member of the protein-tyrosine phosphatase family. DUSP23 is a protein phosphatase which facilitates dephosphorylation of phosphorylated proteins on Tyr and Ser/Thr residues. In vitro, DUSP23 dephosphorylate p44-ERK1 (MAPK3) but not p54 SAPK-beta (MAPK10). In addition, DUSP23 enhances activation of JNK and p38(MAPK14).
DUSP23 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 170 amino acids (1-150 a.a) and having a molecular mass of 18.8kDa.DUSP23 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | Protein phosphatase that mediates dephosphorylation of proteins phosphorylated on Tyr and Ser/Thr residues. In vitro, it can dephosphorylate p44-ERK1 (MAPK3) but not p54 SAPK-beta (MAPK10) in vitro. Able to enhance activation of JNK and p38 (MAPK14). |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9BVJ7 |
| NCBI GenInfo Identifier: | 73620828 |
| NCBI Gene ID: | 54935 |
| NCBI Accession: | Q9BVJ7.1 |
| UniProt Secondary Accession: | Q9BVJ7,Q9NX48 |
| UniProt Related Accession: | Q9BVJ7 |
| Molecular Weight: | 16,588 Da |
| NCBI Full Name: | Dual specificity protein phosphatase 23 |
| NCBI Synonym Full Names: | dual specificity phosphatase 23 |
| NCBI Official Symbol: | DUSP23�� |
| NCBI Official Synonym Symbols: | VHZ; MOSP; LDP-3; DUSP25�� |
| NCBI Protein Information: | dual specificity protein phosphatase 23 |
| UniProt Protein Name: | Dual specificity protein phosphatase 23 |
| UniProt Synonym Protein Names: | Low molecular mass dual specificity phosphatase 3; LDP-3; VH1-like phosphatase Z |
| Protein Family: | Dual specificity protein phosphatase |
| UniProt Gene Name: | DUSP23�� |
| UniProt Entry Name: |
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