Description
Product Name: | Nanodisc Human DRD5-Strep Protein |
SKU: | HDFP961 |
Size: | 10μg |
Target: | DRD5 |
Tag: | C-Flag&Strep Tag |
Expression Host: | HEK293 |
Conjugate: | Unconjugated |
Synonyms: | DBDR, DRD1B, DRD1L2 |
Protein Families: | GPCR, Transmembrane, Druggable Genome. |
Protein Description: | Human DRD5-Strep full length protein-synthetic nanodisc |
Protein Pathways: | GPCRDB Class A Rhodopsin-like, Monoamine GPCRs, G-Protein Coupled Receptors Signaling Pathway. |
Molecular Weight: | The human full length DRD5-Strep protein has a MW of 53 kDa |
This gene encodes the D5 subtype of the dopamine receptor. The D5 subtype is a G-protein coupled receptor which stimulates adenylyl cyclase. This receptor is expressed in neurons in the limbic regions of the brain. It has a 10-fold higher affinity for dopamine than the D1 subtype. Pseudogenes related to this gene reside on chromosomes 1 and 2. [provided by RefSeq, Jul 2008]
Uniprot ID: | P21918 |
Formulation & Reconstitution: | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
Storage & Shipping: | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Usage: | Research use only |