Human DNTTIP1 Recombinant Protein (RPPB3367)
- SKU:
- RPPB3367
- Product Type:
- Recombinant Protein
- Species:
- Human
- Uniprot:
- Q9H147
Frequently bought together:
Description
| Product Name: | Human DNTTIP1 Recombinant Protein |
| Product Code: | RPPB3367 |
| Size: | 20µg |
| Species: | Human |
| Target: | DNTTIP1 |
| Synonyms: | Deoxynucleotidyltransferase Terminal Interacting Protein 1, Novel Protein Similar To Synaptotagmin 1, Terminal Deoxynucleotidyltransferase-Interacting Factor 1, Chromosome 20 Open Reading Frame 167, Tdif1, C20orf167, TdT-Interacting Factor 1, TdT Binding Protein, dJ447F3.4, TDIF1. |
| Source: | Escherichia Coli |
| Physical Appearance: | Sterile Filtered clear solution. |
| Formulation: | The DNTTIP1 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 1mM DTT and 20% glycerol. |
| Stability: | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles. |
| Purity: | Greater than 85.0% as determined by SDS-PAGE. |
| Amino Acid Sequence: | MGSSHHHHHH SSGLVPRGSH MGSMGATGDA EQPRGPSGAE RGGLELGDAG AAGQLVLTNP WNIMIKHRQV QRRGRRSQMT TSFTDPAISM DLLRAVLQPS INEEIQTVFN KYMKFFQKAA LNVRDNVGEE VDAEQLIQEA CRSCLEQAKL LFSDGEKVIP RLTHELPGIK RGRQAEEECA HRGSPLPKKR KGRPPGHILS SDRAAAGMVW KPKSCEPIRR EGPKWDPARL NESTTFVLGS RANKALGMGG TRGRIYIKHP HLFKYAADPQ DKHWLAEQHH MRATGGKMAY LLIEEDIRDL AASDDYRGCL DLKLEELKSF VLPSWMVEKM RKYMETLRTE NEHRAVEAPP QT |
DNTTIP1 binds DNA and increases the activity of terminal deoxynucleotidyltransferase (TDT or DNTT), a DNA polymerase which catalyzes the polymerization of DNA in the absence of a DNA template.
DNTTIP1 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 352 amino acids (1-329) and having a molecular mass of 39.0kDa.DNTTIP1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
| UniProt Protein Function: | DNTTIP1: Shown to enhance TdT activity, in vitro. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 20q13.12 Cellular Component: histone deacetylase complex; nucleolus; nucleoplasm; nucleus Molecular Function:DNA binding; nucleosome binding; protein binding; protein homodimerization activity |
| NCBI Summary: | DNTTIP1 binds DNA and enhances the activity of terminal deoxynucleotidyltransferase (TDT, or DNTT; MIM 187410), a DNA polymerase that catalyzes the polymerization of DNA in the absence of a DNA template (Yamashita et al., 2001 [PubMed 11473582]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q9H147 |
| NCBI GenInfo Identifier: | 26400504 |
| NCBI Gene ID: | 116092 |
| NCBI Accession: | Q9H147.2 |
| UniProt Secondary Accession: | Q9H147,Q96DE3, Q9BQP2, Q9H148, B2RA18, |
| UniProt Related Accession: | Q9H147 |
| Molecular Weight: | 37,013 Da |
| NCBI Full Name: | Deoxynucleotidyltransferase terminal-interacting protein 1 |
| NCBI Synonym Full Names: | deoxynucleotidyltransferase terminal interacting protein 1 |
| NCBI Official Symbol: | DNTTIP1�� |
| NCBI Official Synonym Symbols: | Tdif1; C20orf167; dJ447F3.4�� |
| NCBI Protein Information: | deoxynucleotidyltransferase terminal-interacting protein 1 |
| UniProt Protein Name: | Deoxynucleotidyltransferase terminal-interacting protein 1 |
| UniProt Synonym Protein Names: | Terminal deoxynucleotidyltransferase-interacting factor 1; TdIF1 |
| Protein Family: | Deoxynucleotidyltransferase terminal-interacting protein |
| UniProt Gene Name: | DNTTIP1�� |
| UniProt Entry Name: | TDIF1_HUMAN |
