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Human DNA replication factor Cdt1 ELISA Kit

SKU:
HUFI01276
Product Type:
ELISA Kit
Size:
96 Assays
Uniprot:
Q9H211
Sensitivity:
18.75pg/ml
Range:
31.25-2000pg/ml
ELISA Type:
Sandwich
Synonyms:
CDT1, DNA replication factor Cdt1, Double parked homolog, DUP, RIS2
Reactivity:
Human
Research Area:
Cell Cycle
€599
Frequently bought together:

Description

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Human DNA replication factor Cdt1 ELISA Kit

DNA replication factor CDT1 protein aids in the creation of the pre-replication complex, which is required for DNA replication. CDT1 has the ability to bind geminin, a replication inhibitor, and may be used to block this protein from starting replication at inappropriate sources. The breakdown of the protein is caused by phosphorylation by cyclin A-dependent kinases. Meier-Gorlin Syndrome 4 and Meier-Gorlin Syndrome 1 are two diseases linked to CDT1. CDK-mediated phosphorylation and removal of Cdc6, as well as E2F-mediated DNA replication control, are two related mechanisms of DNA replication factor Cdt1.